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- Title
Still's Disease in the Constellation of Hyperinflammatory Syndromes: A Link with Kawasaki Disease?
- Authors
Dusser, Perrine; Koné-Paut, Isabelle
- Abstract
Still's disease and Kawasaki disease (KD) today belong to the group of cytokine storm syndromes, a pathophysiological set related to excessive activation of the innate immune response. We present here a personal vision of what can link these two diseases, taking up their concepts at their beginning. By their many clinical and physiopathological similarities, we conclude that they constitute a common spectrum whose fate is modified by subtle differences in terms of adaptive response that could, in part, be driven by genetic factors.
- Subjects
JUVENILE idiopathic arthritis; CYTOKINE release syndrome; MUCOCUTANEOUS lymph node syndrome; IMMUNE response
- Publication
Journal of Clinical Medicine, 2021, Vol 10, Issue 15, p3244
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm10153244