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- Title
Karpal Tünel Sendromu Cerrahisi Uygulanan Hastalarda Pnömotik Turnikenin Serum TAS, TOS, MDA ve GSH Seviyeleri Üzerine Etkileri.
- Authors
SEMİS, Halil Sezgin; ÇELİK, Sinan; KEKEÇ, Ahmet Fevzi
- Abstract
This study was designed to reveal the changes in serum total oxidative stress (TOS), total antioxidant status (TAS), malondialdehyde (MDA) and glutathione (GSH) levels of pneumatic tourniquet application at different times of tourniquet in 25 patients who underwent carpal tunnel syndrome surgery. Twenty-five patients who were diagnosed with carpal tunnel syndrome and underwent surgical intervention were included in the study, and pneumatic tourniquets were applied to all patients. The blood taken from the patients 10 minutes before the tourniquet application, 20 minutes after the tourniquet application and 10 minutes after the tourniquet was opened, was centrifuged at 3500 rpm and the serum was removed. TOS, TAS, MDA and GSH levels of serums obtained were measured in a spectrophotometer using the colorimetric method. The results obtained from the patients showed that MDA and TOS levels increased and GSH and TAS levels decreased after tourniquet applications. As a result, how the ischemia due to tourniquet application, which is applied to increase surgical comfort, and reperfusion that will develop after the tourniquet is opened, on serum TOS, TAS, MDA and GSH levels in carpal tunnel surgery syndrome surgeries, which are frequently seen and commonly performed on patients with diagnosed today, change was determined by this study.
- Publication
Gümüshane Üniversitesi Saglik Bilimleri Dergisi, 2022, Vol 11, Issue 3, p1024
- ISSN
2146-9954
- Publication type
Article
- DOI
10.37989/gumussagbil.1118587