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- Title
Obesity: More Than an Inflammatory, an Infectious Disease?
- Authors
Leocádio, Paola C. L.; Oriá, Reinaldo B.; Crespo-Lopez, Maria Elena; Alvarez-Leite, Jacqueline I.
- Abstract
Much is discussed if obesity or diet components modify the "healthy" microbiota or if microbiota modifications trigger events that culminate in obesity. One of the first studies linking obesity and microbiota was conducted by Ley et al. ([7]), showing that obesity is associated with a specific microbiota profile. Considering the relatively well-established relationship between microbiota and obesity in preclinical studies, additional efforts are necessary for the development of clinical interventions that support the microbiota manipulation as a realistic alternative to combat obesity. 35 Cani, PD, Bibiloni, R, Knauf, C, Waget, A, Neyrinck, AM, Delzenne, NM, Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice.
- Subjects
ADIPOSE tissue diseases; COMMUNICABLE diseases; OBESITY; CHYLOMICRONS; NF-kappa B; INTESTINAL physiology; FECAL microbiota transplantation
- Publication
Frontiers in Immunology, 2020, Vol 10, p1
- ISSN
1664-3224
- Publication type
Article
- DOI
10.3389/fimmu.2019.03092