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- Title
Vitamin D Status in Egyptian Children With Allergic Rhinitis.
- Authors
Saad, Khaled; Abdelmoghny, Abobakr; Aboul-Khair, Mohamed Diab; Abdel-Raheem, Yasser Farouk; Gad, Eman Fathalla; Hammour, Ahmed El-Sayed; Hawary, Bahaa; Zahran, Asmaa M.; Alblihed, Mohamd A.; Elhoufey, Amira
- Abstract
Objective: This study aimed to assess the serum levels of vitamin D in an Egyptian cohort of children with allergic rhinitis (AR) and to evaluate any correlation of vitamin D status with the disease severity. Patient and methods: One hundred twenty children with AR and 100 healthy children were included in our study. We studied the serum levels of vitamin D 25(OH)D and 1,25(OH)2D in all participants. The associations between vitamin D levels and clinical characteristics of AR were examined. Results: In AR group, the serum levels of calcium, (25(OH)D and 1,25(OH)2D levels were significantly lower (p <.0001, p <.001, and p <.0001, respectively) in AR children than in controls. Furthermore, the mean 25-OHD3 levels in patients with moderate/severe AR were significantly lower than those with mild AR (p <.001). We found significant negative correlations between mean 25(OH)D levels and total nasal symptom score (r = −.62, p =.002) and total immunoglobulin E levels (r = −.27, p =.013) in AR group. Conclusions: Vitamin D deficiency is a frequent finding among Egyptian children with AR when compared to the healthy group. A significant inverse association was observed between vitamin D levels and AR disease severity.
- Subjects
EGYPT; ACADEMIC medical centers; CALCIUM; IMMUNOGLOBULINS; RHINITIS; SERUM; VITAMIN D; SEVERITY of illness index; CASE-control method; DESCRIPTIVE statistics
- Publication
ENT: Ear, Nose & Throat Journal, 2020, Vol 99, Issue 8, p508
- ISSN
0145-5613
- Publication type
Article
- DOI
10.1177/0145561319850814