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- Title
Comparison of Muscle Mass Indices Using Computed Tomography or Dual X-Ray Absorptiometry for Predicting Physical Performance in Hemodialysis Patients.
- Authors
Kang, Seok Hui; Lee, Hyun Seok; Lee, Sukyung; Cho, Ji-Hyung; Kim, Jun Chul
- Abstract
Background/Aims: Our study aims to evaluate the association between thigh muscle crosssectional area (TMA) using computed tomography (CT), or appendicular skeletal muscle mass (ASM) using dual energy X-ray absorptiometry (DEXA), and physical performance levels in hemodialysis (HD) patients. Methods: Patients were included if they were on HD for ≥6 months (n = 84). ASM and TMA were adjusted to body weight (BW, kg) or height² (Ht², m²). Each participant performed a short physical performance battery test (SPPB), a sit-to-stand for 30 second test (STS30), a 6-minute walk test (6-MWT), a timed up and go test (TUG), and hand grip strength (HGS) test. Results: Correlation coefficients for SPPB, GS, 5STS, STS30, 6-MWT, and TUG were highest in TMA/BW. Results from partial correlation or linear regression analyses displayed similar trends to those derived from Pearson's correlation analyses. An increase in TMA/BW or TMA/Ht2 was associated with a decreased odds ratio of low SPPB, GS, or HGS in multivariate analyses. Indices using DEXA were associated with a decreased odds ratio of a low HGS only in multivariate analysis. Conclusion: TMA indices using CT may be more valuable in predicting physical performance or strength in HD patients.
- Subjects
HEMODIALYSIS patients; MUSCLE mass; COMPUTED tomography; DUAL-energy X-ray absorptiometry; GRIP strength
- Publication
Kidney & Blood Pressure Research, 2018, Vol 42, Issue 6, p1119
- ISSN
1420-4096
- Publication type
Article
- DOI
10.1159/000485779