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- Title
Coronaviruses and gastrointestinal symptoms: an old liaison for the new SARS-CoV-2.
- Authors
Caio, Giacomo; Lungaro, Lisa; Cultrera, Rosario; De Giorgio, Roberto; Volta, Umberto
- Abstract
The coronavirus disease (Covid-19) has caused a pandemic with more than 600,000 deaths to date. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the beta-coronavirus genus that also includes SARS and the Middle East Respiratory Syndrome Coronavirus (MERS). While the typical presentation is given by respiratory symptoms and fever, some patients also report gastrointestinal symptoms such as diarrhea, nausea, vomiting, and abdominal pain. Several studies have identified the SARS-CoV-2 RNA in stool specimens of infected patients, and its viral receptor angiotensin-converting enzyme 2 (ACE2) is highly expressed in enterocytes. In this short review, we report the frequency of gastrointestinal symptoms in infected patients and suggest possible implications for disease management, transmission, and infection control.
- Subjects
FECAL analysis; ABDOMINAL pain; ANGIOTENSIN converting enzyme; PREVENTION of communicable diseases; CORONAVIRUSES; DIARRHEA; GASTROINTESTINAL diseases; INTESTINAL mucosa; NAUSEA; VOMITING; DISEASE management; COVID-19; SYMPTOMS
- Publication
Gastroenterology & Hepatology from Bed to Bench, 2020, Vol 13, Issue 4, p341
- ISSN
2008-2258
- Publication type
Article