We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Visible‐Light‐Driven Four‐Component Radical Relay Aminocarbonylation of Unactivated Alkenes<sup>†</sup>.
- Authors
Lu, Bin; Bao, Feng‐Shuo; He, Zi‐Wei; Xiao, Wen‐Jing; Chen, Jia‐Rong
- Abstract
Comprehensive Summary: Catalytic four‐component radical carbonylation of unactivated alkenes has recently been recognized as a robust protocol for rapid construction of various structurally diverse carbonyl compounds. Given the significance of fluorine‐containing groups, this reaction class has been extensively applied to assembly of a variety of perfluoroalkyl carboxylic acid derivatives by transition metal catalysis. Herein, we report a visible‐light‐driven radical relay 1,2‐perfluoroalkylation aminocarbonylation of unactivated alkenes using CO gas as carbonyl source and 4CzIPN as organic photocatalyst. A wide range of alkenes and amines were well tolerated, providing the valuable β‐perfluoroalkylated amides with generally good yields and high chemoselectivity.
- Subjects
RADICALS (Chemistry); CARBOXYLIC acid derivatives; AMIDES; CARBOXYLIC acids; CARBONYL compounds; TRANSITION metals; CARBONYLATION
- Publication
Chinese Journal of Chemistry, 2024, Vol 42, Issue 9, p990
- ISSN
1001-604X
- Publication type
Article
- DOI
10.1002/cjoc.202300733