We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Blinded Case-Control Study of the Relationship between Human Coronavirus NL63 and Kawasaki Syndrome.
- Authors
Dominguez, Samuel R.; Anderson, Marsha S.; Glodé, Mary P.; Robinson, Christine C.; Holmes, Kathryn V.
- Abstract
We conducted a blinded, case-control, retrospective study in pediatric patients hospitalized at The Children's Hospital, Denver, Colorado, to determine whether human coronavirus (HCoV)—NL63 infection is associated with Kawasaki syndrome (KS). Over the course of a 7-month period, nasopharyngeal-wash samples from 2 (7.7%) of 26 consecutive children with KS and 4 (7.7%) of 52 matched control subjects tested positive for HCoV-NL63 by reverse transcription-polymerase chain reaction. These data suggest that, although HCoV-NL63 was circulating in children in our community during the time of the study, the prevalence of infection with HCoV-NL63 was not greater in patients with KS than in control subjects.
- Subjects
COLORADO; CORONAVIRUS diseases; MUCOCUTANEOUS lymph node syndrome; JUVENILE diseases; PEDIATRICS; POLYMERASE chain reaction; NASOPHARYNX examination; CHILDREN
- Publication
Journal of Infectious Diseases, 2006, Vol 194, Issue 12, p1697
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1086/509509