OpenURL Connection Search

Select item for more details and to access through your institution.

Genetic studies on chromosome 12 in late-onset Alzheimer disease.
Published in:
1998
By:
- Wu, William S.;
- Holmans, Peter;
- Wavrant-DeVrieze, Fabienne;
- Shears, Shantia;
- Kehoe, Patrick;
- Crook, Richard;
- Booth, Jeremy;
- Williams, Nigel;
- Perez-Tur, Jordi;
- Roehl, Kimberely;
- Fenton, Iain;
- Chartier-Harlin, Marie-Christine;
- Lovestone, Simon;
- Williams, Julie;
- Hutton, Mike;
- Hardy, John;
- Owen, Michael J.;
- Goate, Alison;
- Wu, W S;
- Holmans, P
Publication type:
journal article
Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
Published in:
Molecular Psychiatry, 2013, v. 18, n. 12, p. 1302, doi. 10.1038/mp.2012.142
By:
- Green, E K;
- Hamshere, M;
- Forty, L;
- Gordon-Smith, K;
- Fraser, C;
- Russell, E;
- Grozeva, D;
- Kirov, G;
- Holmans, P;
- Moran, J L;
- Purcell, S;
- Sklar, P;
- Owen, M J;
- O'Donovan, M C;
- Jones, L;
- Jones, I R;
- Craddock, N
Publication type:
Article
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.
Published in:
Molecular Psychiatry, 2013, v. 18, n. 6, p. 708, doi. 10.1038/mp.2012.67
By:
- Hamshere, M L;
- Walters, J T R;
- Smith, R;
- Richards, A L;
- Green, E;
- Grozeva, D;
- Jones, I;
- Forty, L;
- Jones, L;
- Gordon-Smith, K;
- Riley, B;
- O'Neill, T;
- Kendler, K S;
- Sklar, P;
- Purcell, S;
- Kranz, J;
- Morris, D;
- Gill, M;
- Holmans, P;
- Craddock, N
Publication type:
Article
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.
Published in:
Molecular Psychiatry, 2013, v. 18, n. 6, p. 738, doi. 10.1038/mp.2012.89
By:
- Hamshere, M L;
- Walters, J T R;
- Smith, R;
- Richards, A L;
- Green, E;
- Grozeva, D;
- Jones, I;
- Forty, L;
- Jones, L;
- Gordon-Smith, K;
- Riley, B;
- O'Neill, T;
- Kendler, K S;
- Sklar, P;
- Purcell, S;
- Kranz, J;
- Morris, D;
- Gill, M;
- Holmans, P;
- Craddock, N
Publication type:
Article
Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.
Published in:
Molecular Psychiatry, 2012, v. 17, n. 10, p. 996, doi. 10.1038/mp.2011.117
By:
- Lips, E S;
- Cornelisse, L N;
- Toonen, R F;
- Min, J L;
- Hultman, C M;
- Holmans, P A;
- O'Donovan, M C;
- Purcell, S M;
- Smit, A B;
- Verhage, M;
- Sullivan, P F;
- Visscher, P M;
- Posthuma, D
Publication type:
Article
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.
Published in:
Molecular Psychiatry, 2012, v. 17, n. 2, p. 142, doi. 10.1038/mp.2011.154
By:
- Kirov, G;
- Pocklington, A J;
- Holmans, P;
- Ivanov, D;
- Ikeda, M;
- Ruderfer, D;
- Moran, J;
- Chambert, K;
- Toncheva, D;
- Georgieva, L;
- Grozeva, D;
- Fjodorova, M;
- Wollerton, R;
- Rees, E;
- Nikolov, I;
- van de Lagemaat, L N;
- Bayés, À;
- Fernandez, E;
- Olason, P I;
- Böttcher, Y
Publication type:
Article
Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain.
Published in:
Molecular Psychiatry, 2012, v. 17, n. 2, p. 193, doi. 10.1038/mp.2011.11
By:
- Richards, A L;
- Jones, L;
- Moskvina, V;
- Kirov, G;
- Gejman, P V;
- Levinson, D F;
- Sanders, A R;
- Purcell, S;
- Visscher, P M;
- Craddock, N;
- Owen, M J;
- Holmans, P;
- O'Donovan, M C
Publication type:
Article
Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
Published in:
Molecular Psychiatry, 2011, v. 16, n. 1, p. 2, doi. 10.1038/mp.2009.107
By:
- Y. Liu;
- Blackwood, D. H.;
- Caesar, S.;
- de Geus, E. J. C.;
- Farmer, A.;
- Ferreira, M. A. R.;
- Ferrier, I. N.;
- Fraser, C.;
- Gordon-Smith, K.;
- Green, E. K.;
- Grozeva, D.;
- Gurling, H. M.;
- Hamshere, M. L.;
- Heutink, P.;
- Holmans, P A;
- Hoogendijk, W. J.;
- Hottenga, J. J.;
- Jones, L.;
- Jones, I. R.;
- Kirov, G.
Publication type:
Article
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.
Published in:
Molecular Psychiatry, 2011, v. 16, n. 2, p. 202, doi. 10.1038/mp.2009.125
By:
- Shyn, S. I.;
- Shi, J.;
- Kraft, J. B.;
- Potash, J. B.;
- Knowles, J. A.;
- Weissman, M. M.;
- Garriock, H. A.;
- Yokoyama, J. S.;
- McGrath, P. J.;
- Peters, E. J.;
- Scheftner, W. A.;
- Coryell, W.;
- Lawson, W. B.;
- Jancic, D.;
- Gejman, P. V.;
- Sanders, A. R.;
- Holmans, P.;
- Slager, S. L.;
- Levinson, D. F.;
- Hamilton, S. P.
Publication type:
Article
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha.
Published in:
Molecular Psychiatry, 2010, v. 15, n. 11, p. 1101, doi. 10.1038/mp.2009.96
By:
- Carroll, L. S.;
- Williams, N. M.;
- Moskvina, V.;
- Russell, E.;
- Norton, N.;
- Williams, H. J.;
- Peirce, T.;
- Georgieva, L.;
- Dwyer, S.;
- Grozeva, D.;
- Greene, E.;
- Farmer, A.;
- McGuffin, P.;
- Morris, D. W.;
- Corvin, A.;
- Gill, M.;
- Rujescu, D.;
- Sham, P.;
- Holmans, P.;
- Jones, I.
Publication type:
Article
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.
Published in:
Molecular Psychiatry, 2010, v. 15, n. 10, p. 1016, doi. 10.1038/mp.2009.49
By:
- Green, E. K.;
- Grozeva, D.;
- Jones, I.;
- Jones, L.;
- Kirov, G.;
- Caesar, S.;
- Gordon-Smith, K.;
- Fraser, C.;
- Forty, L.;
- Russell, E.;
- Hamshere, M. L.;
- Moskvina, V.;
- Nikolov, I.;
- Farmer, A.;
- McGuffin, P.;
- Holmans, P. A.;
- Owen, M. J.;
- O'Donovan, M. C.;
- Craddock, N.
Publication type:
Article
Meta-analysis of 32 genome-wide linkage studies of schizophrenia.
Published in:
Molecular Psychiatry, 2009, v. 14, n. 8, p. 774, doi. 10.1038/mp.2008.135
By:
- Ng, M. Y. M.;
- Levinson, D. F.;
- Faraone, S. V.;
- Suarez, B. K.;
- DeLisi, L. E.;
- Arinami, T.;
- Riley, B.;
- Paunio, T.;
- Pulver, A. E.;
- Irmansyah;
- Holmans, P. A.;
- Escamilla, M.;
- Wildenauer, D. B.;
- Williams, N. M.;
- Laurent, C.;
- Mowry, B. J.;
- Brzustowicz, L. M.;
- Maziade, M.;
- Sklar, P.;
- Garver, D. L.
Publication type:
Article
Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms.
Published in:
Molecular Psychiatry, 2009, v. 14, n. 8, p. 786, doi. 10.1038/mp.2009.11
By:
- Holmans, P. A.;
- Riley, B.;
- Pulver, A. E.;
- Owen, M. J.;
- Wildenauer, D. B.;
- Gejman, P. V.;
- Mowry, B. J.;
- Laurent, C.;
- Kendler, K. S.;
- Nestadt, G.;
- Williams, N. M.;
- Schwab, S. G.;
- Sanders, A. R.;
- Nertney, D.;
- Mallet, J.;
- Wormley, B.;
- Lasseter, V. K.;
- O'Donovan, M. C.;
- Duan, J.;
- Albus, M.
Publication type:
Article
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
Published in:
Molecular Psychiatry, 2009, v. 14, n. 3, p. 252, doi. 10.1038/mp.2008.133
By:
- Moskvina, V.;
- Craddock, N.;
- Holmans, P.;
- Nikolov, I.;
- Pahwa, J. S.;
- Green, E.;
- Owen, M. J.;
- O'Donovan, M. C.
Publication type:
Article
Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2.
Published in:
Molecular Psychiatry, 2009, v. 14, n. 1, p. 30, doi. 10.1038/mp.2008.108
By:
- O'Donovan, M. C.;
- Norton, N.;
- Williams, H.;
- Peirce, T.;
- Moskvina, V.;
- Nikolov, I.;
- Hamshere, M.;
- Carroll, L.;
- Georgieva, L.;
- Dwyer, S.;
- Holmans, P.;
- Marchini, J. L.;
- Spencer, C. C. A.;
- Howie, B.;
- Leung, H.-T.;
- Giegling, I.;
- Hartmann, A. M.;
- Möller, H.-J.;
- Morris, D. W.;
- Shi, Y.
Publication type:
Article
A genome-wide screen for linkage in Nordic sib-pairs with multiple sclerosis.
Published in:
Genes & Immunity, 2002, v. 3, n. 5, p. 279, doi. 10.1038/sj.gene.6363866
By:
- Akesson, E.;
- Oturai, A.;
- Berg, J.;
- Fredrikson, S.;
- Andersen, O.;
- Harbo, H.F.;
- Laaksonen, M.;
- Myhr, K.M.;
- Nyland, H.I.;
- Ryder, L.P.;
- Sandberg-Wollheim, N.;
- Sorensen, P.S.;
- Spurkland, A.;
- Svejgaard, A.;
- Holmans, P.;
- Compston, A.;
- Hillert, J.;
- Sawcer, S.
Publication type:
Article
Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington’s disease.
Published in:
Genes, Brain & Behavior, 2008, v. 7, n. 3, p. 288, doi. 10.1111/j.1601-183X.2007.00350.x
By:
- Hodges, A.;
- Hughes, G.;
- Brooks, S.;
- Elliston, L.;
- Holmans, P.;
- Dunnett, S. B.;
- Jones, L.
Publication type:
Article
Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01678-z
By:
- Dimitriadis, S. I.;
- Perry, G.;
- Foley, S. F.;
- Tansey, K. E.;
- Jones, D. K.;
- Holmans, P.;
- Zammit, S.;
- Hall, J.;
- O'Donovan, M. C.;
- Owen, M. J.;
- Singh, K. D.;
- Linden, D. E.
Publication type:
Article
Design of Case-controls Studies with Unscreened Controls.
Published in:
Annals of Human Genetics, 2005, v. 69, n. 5, p. 566, doi. 10.1111/j.1529-8817.2005.00175.x
By:
- Moskvina, V.;
- Holmans, P.;
- Schmidt, K. M.;
- Craddock, N.
Publication type:
Article
Allowing for Genotyping Error in Analysis of Unmatched Case-Control Studies.
Published in:
Annals of Human Genetics, 2003, v. 67, n. 2, p. 165, doi. 10.1046/j.1469-1809.2003.00020.x
By:
- Rice, K.M.;
- Holmans, P.
Publication type:
Article
Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.
Published in:
2006
By:
- Smemo S;
- Nowotny P;
- Hinrichs AL;
- Kauwe JS;
- Cherny S;
- Erickson K;
- Myers AJ;
- Kaleem M;
- Marlowe L;
- Gibson AM;
- Hollingworth P;
- O'Donovan MC;
- Morris CM;
- Holmans P;
- Lovestone S;
- Morris JC;
- Thal L;
- Li Y;
- Grupe A;
- Hardy J
Publication type:
Journal Article
Exome arrays capture polygenic rare variant contributions to schizophrenia.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 5, p. 1001, doi. 10.1093/hmg/ddv620
By:
- Richards, A. L.;
- Leonenko, G.;
- Walters, J. T.;
- Kavanagh, D. H.;
- Rees, E. G.;
- Evans, A.;
- Chambert, K. D.;
- Moran, J. L.;
- Goldstein, J.;
- Neale, B. M.;
- McCarroll, S. A.;
- Pocklington, A. J.;
- Holmans, P. A.;
- Owen, M. J.;
- O'Donovan, M. C.
Publication type:
Article
Stage 2 of the Wellcome Trust UK–Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16–q21, 4q12–q21, 9p21, 10p14–p12 and 18q22.
Published in:
2006
By:
- Lambert, D;
- Middle, F;
- Hamshere, M L;
- Segurado, R;
- Raybould, R;
- Corvin, A;
- Green, E;
- O'Mahony, E;
- Nikolov, I;
- Mulcahy, T;
- Haque, S;
- Bort, S;
- Bennett, P;
- Norton, N;
- Owen, M J;
- Kirov, G;
- Lendon, C;
- Jones, L;
- Jones, I;
- Holmans, P
Publication type:
Correction Notice
Stage 2 of the Wellcome Trust UK–Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16–q21, 4q12–q21, 9p21, 10p14–p12 and 18q22.
Published in:
Molecular Psychiatry, 2005, v. 10, n. 9, p. 831, doi. 10.1038/sj.mp.4001684
By:
- Lambert, D.;
- Middle, F.;
- Hamshere, M. L.;
- Segurado, R.;
- Raybould, R.;
- Corvin, A.;
- Green, E.;
- O'Mahony, E.;
- Nikolov, I;
- Mulcahy, T.;
- Haque, S.;
- Bort, S.;
- Bennett, P.;
- Norton, N.;
- Owen, M. J.;
- Kirov, G.;
- Lendon, C.;
- Jones, L.;
- Jones, I.;
- Holmans, P.
Publication type:
Article
Multicenter linkage study of schizophrenia loci on chromosome 22q.
Published in:
Molecular Psychiatry, 2004, v. 9, n. 8, p. 784, doi. 10.1038/sj.mp.4001481
By:
- Mowry, B. J.;
- Holmans, P. A.;
- Pulver, A. E.;
- Gejman, P. V.;
- Riley, B.;
- Williams, N. M.;
- Laurent, C.;
- Schwab, S. G.;
- Wildenauer, D. B.;
- Bauché, S.;
- Owen, M. J.;
- Wormley, B.;
- Sanders, A. R.;
- Nestadt, G.;
- Liang, K. Y.;
- Duan, J.;
- Ribble, R.;
- Norton, N.;
- Soubigou, S.;
- Maier, W.
Publication type:
Article
Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12.
Published in:
Molecular Psychiatry, 2003, v. 8, n. 3, p. 288, doi. 10.1038/sj.mp.4001277
By:
- McInnis, M. G.;
- Lan, T.-H.;
- Willour, V. L.;
- McMahon, F. J.;
- Simpson, S. G.;
- Addington, A. M.;
- MacKinnon, D. F.;
- Potash, J. B.;
- Mahoney, A. T.;
- Chellis, J.;
- Huo, Y.;
- Swift-Scanlan, T.;
- Chen, H.;
- Koskela, R.;
- Colin Stine, O.;
- Jamison, K. R.;
- Holmans, P.;
- Folstein, S. E.;
- Ranade, K.;
- Friddle, C.
Publication type:
Article
Autosome search for schizophrenia susceptibility genes in multiply affected families.
Published in:
Molecular Psychiatry, 1999, v. 4, n. 4, p. 353, doi. 10.1038/sj.mp.4000521
By:
- Rees, M.I.;
- Fenton, I.;
- Williams, N.M.;
- Holmans, P.;
- Norton, N.;
- Cardno, A.;
- Asherson, P.;
- Spurlock, G.;
- Roberts, E.;
- Parfitt, E.;
- Mant, R.;
- Vallada, H.;
- Dawson, E.;
- Li, M.-W.;
- Collier, D.A.;
- Powell, J.F.;
- Nanko, S.;
- Gill, M.;
- McGuffin, P.
Publication type:
Article
A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia.
Published in:
1998
By:
- Williams, J.;
- Spurlock, G.;
- Holmans, P.;
- Mant, R.;
- Murphy, K.;
- Jones, L.;
- Cardno, A.;
- Asherson, P.;
- Blackwood, D.;
- Muir, W.;
- Meszaros, K.;
- Aschauer, H.;
- Mallet, J.;
- Laurent, C.;
- Pekkarinen, P.;
- Seppala, J.;
- Stefanis, C.N.;
- Papadimitriou, G.N.;
- Macciardi, F.
Publication type:
Correction Notice
A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia.
Published in:
Molecular Psychiatry, 1998, v. 3, n. 2, p. 141, doi. 10.1038/sj.mp.4000376
By:
- Williams, J.;
- Spurlock, G.;
- Holmans, P.;
- Mant, R.;
- Murphy, K.;
- Jones, L.;
- Cardno, A.;
- Asherson, P.;
- Blackwood, D.;
- Muir, W.;
- Meszaros, K.;
- Aschauer, H.;
- Mallet, J.;
- Laurent, C.;
- Pekkarinen, P.;
- Seppala, J.;
- Stefanis, C.N.;
- Papadimitriou, G.N.;
- Macciardi, F.
Publication type:
Article
A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter.
Published in:
Molecular Psychiatry, 1998, v. 3, n. 1, p. 42, doi. 10.1038/sj.mp.4000342
By:
- Spurlock, G.;
- Heils, A.;
- Holmans, P.;
- Williams, J.;
- D'Souza, U.M.;
- Cardno, A.;
- Murphy, K.C.;
- Jones, L.;
- Buckland, P.R.;
- McGuffin, P.;
- Lesch, K.P.;
- Owen, M.J.
Publication type:
Article
Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT).
Published in:
Molecular Psychiatry, 1997, v. 2, n. 5, p. 398, doi. 10.1038/sj.mp.4000256
By:
- Rees, M.;
- Norton, N.;
- Jones, I.;
- McCandless, F.;
- Scourfield, J.;
- Holmans, P.;
- Moorhead, S.;
- Feldman, E.;
- Sadler, S.;
- Cole, T.;
- Redman, K.;
- Farmer, A.;
- McGuffin, P.;
- Owen, M.J.;
- Craddock, N.
Publication type:
Article
Association studies in psychiatric genetics.
Published in:
Molecular Psychiatry, 1997, v. 2, n. 4, p. 270, doi. 10.1038/sj.mp.4000292
By:
- Owen, M.J.;
- Holmans, P.;
- McGuffin, P.
Publication type:
Article
A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs.
Published in:
Human Molecular Genetics, 1999, v. 8, n. 9, p. 1729, doi. 10.1093/hmg/8.9.1729
By:
- Williams, N. M.;
- Rees, M. I.;
- Holmans, P.;
- Norton, N.;
- Cardno, A.G.;
- Jones, L.A.;
- Murphy, K.C.;
- Sanders, R.D.;
- McCarthy, G.;
- Gray, M.Y.;
- Fenton, I.;
- McGuffin, P.;
- Owen, M.J.
Publication type:
Article
Dopa-responsive dystonia: A clinical and molecular genetic study.
Published in:
Annals of Neurology, 1998, v. 44, n. 4, p. 649, doi. 10.1002/ana.410440411
By:
- Bandmann, O.;
- Valente, E. M.;
- Holmans, P.;
- Surtees, R. A. H.;
- Walters, J. H.;
- Wevers, R. A.;
- Marsden, C. D.;
- Wood, N. W.
Publication type:
Article
Genome scan for association and linkage.
Published in:
Genetic Epidemiology, 1995, v. 12, n. 6, p. 613, doi. 10.1002/gepi.1370120615
By:
- Holmans, P.;
- McGuffin, P.;
- Clayton, D.
Publication type:
Article
Detailed genotyping demonstrates association between the slow acetylator genotype for N-acetyltransferase 2 (NAT2) and familial Parkinson's disease.
Published in:
2000
By:
- Bandmann, Oliver;
- Vaughan, Jenny R.;
- Holmans, Peter;
- Marsden, C. David;
- Wood, Nicholas W.;
- Bandmann, O;
- Vaughan, J R;
- Holmans, P;
- Marsden, C D;
- Wood, N W
Publication type:
journal article
Effect of Genotyping Error on Type-I Error Rate of Affected Sib Pair Studies with Genotyped Parents.
Published in:
Human Heredity, 2005, v. 59, n. 3, p. 157, doi. 10.1159/000085939
By:
- Seaman, S.R.;
- Holmans, P.
Publication type:
Article

Found: 37