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- Title
Percutaneous Cementoplasty in the Palliative, Multimodal Treatment of Primary Bone Tumors of the Distal Aspect of the Radius in Four Dogs.
- Authors
BÖTTCHER, PETER; KRASTEL, DOROTHEE; HIERHOLZER, JOHANNES; WESTPHALEN, KERSTIN; FLORIAN, STEPHANIE; HILDEBRANDT, GUIDO; VERA, GREVEL; OECHTERING, GERHARD
- Abstract
Objective To (1) evaluate the analgesic effect of percutaneous cementoplasty (PC) in dogs with primary bone tumor (PBT) of the distal aspect of the radius and (2) evaluate the impact on the course of disease by adding PC to a palliative, multimodal treatment protocol in these dogs. Study Design Prospective pilot study. Animals Dogs (n=4) with PBT of the distal aspect of the radius. Methods Tumor lesions were filled percutaneously with polymethylmethacrylate under fluoroscopic guidance. Pamidronate was administered once in a week before PC. Radiotherapy and chemotherapy were initiated 2 and 6 weeks after PC, respectively. Force plate analysis was performed immediately before 2, and 6 weeks after PC. Survival time was defined from PC to euthanasia. Results Two dogs had a significant increase in peak vertical force 2 weeks after PC ( P=.043) and remained free of lameness for 18 and 20 weeks, respectively. One dog had an acute relapse after an initially lame-free period of 10 days. The remaining dog failed to improve ( P=.686). Three dogs developed at least 2 complications including transient worsening of the lameness after PC, cement leakage, wound infection and suspected thromboembolism in combination with cough and anemia. Median survival was 4.8 months (range, 1–5.7 months). Conclusions PC in combination with pamidronate significantly improved lameness in 2 dogs; however, PC is not risk-free. Deep wound infection, intraarticular cement leakage, and venous thrombosis were the main complications. Clinical Relevance PC might be a useful addition to established palliative, multimodal treatment protocols in dogs with PBT; however, because of the complications encountered PC warrants further study before routine use can be considered.
- Publication
Veterinary Surgery, 2009, Vol 38, Issue 7, p888
- ISSN
0161-3499
- Publication type
Article
- DOI
10.1111/j.1532-950X.2009.00596.x