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- Title
STUDYING THE COMPARISON OF INTRAVENOUS DEXMEDETOMIDINE SEDATION TO PERINEURAL DEXMEDETOMIDINE ON SUPRACLAVICULAR APPROACH BRACHIAL PLEXUS BLOCK DURING UPPER LIMB ORTHOPEDIC SURGERY.
- Authors
Prasad, Parthsarthi; Ekka, Deepa; Bhagat, Shiwani
- Abstract
Background: Dexmedetomidine is frequently used as an adjuvant analgesic in both intrathecal and intravenous infusions. Recently, the role of perineural dexmedetomidine has also been addressed. However, existing literature data is scarce concerning the issue. Aim: The present study aimed to assess the efficacy of intravenous Dexmedetomidine sedation to Perineural Dexmedetomidine on Supraclavicular Approach Brachial Plexus Block during upper limb orthopedic surgery. Methods: 80 subjects were randomly divided into two groups of 40 subjects each where Group I subjects were given 1mcg/kg/IV dexmedetomidine as a loading dose for 10 minutes followed by continuous 0.4mcg/kg/hr IV dexmedetomidine infusion and Group II subjects were given 1mcg/kg perineural dexmedetomidine. In both the groups, duration and onset of motor and sensory block, postoperative analgesia need, hemodynamic parameters, and Ramsay sedation scores were assessed along with any encountered side-effect. Results: Mean sensory block onset was significantly higher in Group I with p<0.05, however, mean motor block onset was comparable in two groups with p>0.05. Motor and sensory blockade duration was significantly longer in Group I (p<0.05). Group I subjects showed lower systolic and diastolic blood pressure and lower pulse rate throughout the duration, and SpO2 levels were comparable. No difference in Ramsay sedation score was seen in either group, however, significantly lesser scores were seen at 9, 12, and 15 hours postoperatively in Group I (p<0.05). Mean analgesia rescue time with VAS >4 was higher in Group I significantly (p<0.05). Conclusions: The present study concludes that early sensory block onset was seen in IV dexmedetomidine with significantly longer duration of analgesia, motor, and sensory block in comparison to perineural dexmedetomidine used as an adjuvant to supraclavicular block using 2% of 5mg/kg Lidocaine and 0.5% of 2mg/kg bupivacaine used for upper limb orthopedic surgeries.
- Subjects
BRACHIAL plexus block; DIASTOLIC blood pressure; SYSTOLIC blood pressure; ORTHOPEDIC surgery; INTRAVENOUS therapy; CONSCIOUS sedation
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 7, p3088
- ISSN
0975-3583
- Publication type
Article