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- Title
Efficacy of oral antibiotics in children with post-operative abscess from perforated appendicitis.
- Authors
Sujka, Joseph A.; Weaver, Katrina L.; Sobrino, Justin A.; Poola, Ashwini; Gonzalez, Katherine W.; St. Peter, Shawn D.
- Abstract
<bold>Background: </bold>Post-operative intra-abdominal abscess (PIAA) is the most common complication after appendectomy for perforated appendicitis (PA). Typically, intravenous antibiotics by a peripherally inserted venous catheter are utilized to treat the abscess. We sought to evaluate the role of oral antibiotics in this population.<bold>Methods: </bold>This is a retrospective review conducted of children between January 2005 and September 2015 with a PIAA. Demographics, clinical course, complications, and follow-up were analyzed using descriptive statistics. Comparative analysis was performed on those who were treated with oral vs IV antibiotics after diagnosis of PIAA.<bold>Results: </bold>103 children were included. Days of symptoms prior to admission were 3.2 ± 2.3 days with a WBC of 17.9 ± 6.4. Median time to diagnosis of PIAA from appendectomy was 7 days (7, 10). Mean total length of stay was 10 ± 3.4 days. 42% were treated with oral antibiotics (n = 43) versus 58% IV antibiotics (n = 60) at the time of discharge. We found a significant increase in total length of hospital stay (9.1 vs 10.7, p = 0.02) and number of medical encounters required for treatment (3.4 vs 4.4, p ≤ 0.01) in the IV group.<bold>Conclusions: </bold>PIAA treatment after appendectomy for PA can be treated with oral antibiotics with equivalent outcomes as IV antibiotic treatment, but with shorter length of hospitalizations and less medical encounters required.
- Subjects
APPENDECTOMY; APPENDICITIS; ANTIBIOTICS; ABSCESSES; LENGTH of stay in hospitals; SYMPTOMS; ABDOMINAL abscess; POSTOPERATIVE care; SURGICAL site infections; TREATMENT effectiveness; RETROSPECTIVE studies
- Publication
Pediatric Surgery International, 2019, Vol 35, Issue 3, p329
- ISSN
0179-0358
- Publication type
journal article
- DOI
10.1007/s00383-018-4424-0