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- Title
Osteoid osteoma and osteoid osteoma-mimicking lesions: biopsy findings, distinctive MDCT features and treatment by radiofrequency ablation.
- Authors
Becce F; Theumann N; Rochette A; Larousserie F; Campagna R; Cherix S; Guillou L; Mouhsine E; Anract P; Drapé JL; Feydy A; Becce, Fabio; Theumann, Nicolas; Rochette, Antoine; Larousserie, Frédérique; Campagna, Raphaël; Cherix, Stéphane; Guillou, Louis; Mouhsine, Elyazid; Anract, Philippe
- Abstract
<bold>Objective: </bold>To report the biopsy findings of osteoid osteoma (OO) and OO-mimicking lesions, assess their distinctive multidetector computed tomography (MDCT) features and evaluate treatment by radiofrequency ablation (RFA).<bold>Methods: </bold>In this multicentric retrospective study, 80 patients (54 male, 26 female, mean age 24.1 years, range 5-48) with presumed (clinical and MDCT features) OO were treated by percutaneous RFA between May 2002 and June 2009. Per-procedural biopsies were always performed. The following MDCT features were assessed: skeletal distribution and location within the bone, size, central calcification, surrounding osteosclerosis and periosteal reaction. Clinical success of RFA was evaluated.<bold>Results: </bold>Histopathological diagnoses were: 54 inconclusive biopsies, 16 OO, 10 OO-mimicking lesions (5 chronic osteomyelitis, 3 chondroblastoma, 1 eosinophilic granuloma, 1 fibrous dysplasia). OO-mimicking lesions were significantly greater in size (p = 0.001) and presented non-significant trends towards medullary location (p = 0.246), moderate surrounding osteosclerosis (p = 0.189) and less periosteal reaction (p = 0.197), compared with OO. Primary success for ablation of OO-mimicking lesions was 100% at 1 month, 85.7% at 6 and 12 months, and 66.7% at 24 months. Secondary success was 100%.<bold>Conclusion: </bold>Larger size, medullary location, less surrounding osteosclerosis and periosteal reaction on MDCT may help differentiate OO-mimicking lesions from OO. OO-mimicking lesions are safely and successfully treated by RFA.
- Publication
European Radiology, 2010, Vol 20, Issue 10, p2439
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-010-1811-x