We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A randomized controlled trial evaluating the efficacy and safety of a MYCOFUNGI CREAM in patients with skin mycoses.
- Authors
Youmsi Fokouo, Roger Ducos; Tsouh Fokou, Patrick Valere; Choakem, Grace; Nhanag, Samuel; Majoumouo, Michele Stella; Tamko, Jean-Lucas; Chedjou, Jean Paul; Kuete, Geraldine; Mbacham, Wilfred Fon; Boyom, Fabrice Fekam
- Abstract
Introduction and Objective. Skin mycoses is a neglected condition with low quality of life and morbidity that primarily affects school-aged children in developing nations. Current treatment options have considerable limits, emphasizing the critical need for alternative therapies. The purpose of this clinical trial was to evaluate the potential benefit of Mycofungi cream in individuals with superficial fungal skin infection disorders. Materials and method. Patients with cutaneous mycoses ranging in age from 2-65 years were randomly assigned to either Mycofungi (Syzygium aromaticum (L.) Merr.) cream or Terbinafine creams. Within a four-week follow-up, the rates of cure or improvement were compared between the two groups. An incidental side-effect was also noted. Results. A total of 256 individuals with skin mycoses were preliminarily screened, and 80 eligible participants enrolled and randomly assigned to the Mycofungi (n=40) or Terbinafine (n=40) groups. Overall, 92.5% (37/40) of patients with cutaneous mycoses were asymptomatic or had improved condition following Mycofungi application at the final follow-up appointment. After four weeks of treatment, the clinical cure rate was high and nearly identical in the two groups: 80% in the Mycofungi group and 85% in the Terbinafine group. Both terbinafine and mycofungy were well tolerated. Conclusions. The efficacy of Mycofungi cream (S. aromaticum) in treating or reducing the severity of skin mycoses was proven in this clinical trial. Nonetheless, additional detailed experiments are needed to reach a conclusion on the efficacy of Mycofungi.
- Subjects
DERMATOMYCOSES; CHILDREN; CLINICAL trials; CLOVE tree; TERBINAFINE
- Publication
Journal of Pre-Clinical & Clinical Research, 2022, Vol 16, Issue 2, p27
- ISSN
1898-2395
- Publication type
Article
- DOI
10.26444/jpccr/150090