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- Title
Effect of Endemic Fluorosis on Hematological Parameters.
- Authors
Ersoy, Ismail; Alanoglu, E.; Koroglu, Banu; Varol, Simge; Akcay, Selahaddin; Ugan, Yunus; Ersoy, Sıddıka; Tamer, Mehmet
- Abstract
lthough so many studies exist on effect of fluoride on hematological parameters in experimental animals, a few studies have been conducted to investigate the effects of chronic fluorosis on hematological parameters in humans' subjects with endemic fluorosis. So we aimed to determine the hematological parameters in patients with endemic fluorosis. The study group consisted of 60 patients with endemic fluorosis (27 females, 33 males, and mean age 33.4 ± 9.6 years). An age-, gender-, and body mass index-matched control group was composed of 34 healthy volunteers (11 females, 23 males with a mean age 32.6 ± 5.6 years). Urine fluoride levels of fluorosis patients were significantly higher than control subjects as expected (0.42 ± 0.09 vs 1.92 ± 0.14 mg/l, respectively; P < 0.001). There were no statistically significant differences between the fluorosis group and control group with respect to hematological parameters (complete blood count and ferritin). We concluded that chronic fluorosis has no effect on hematological parameters in patients with endemic fluorosis.
- Subjects
FLUOROSIS; HEMATOLOGICAL manifestations of general diseases; CHRONIC diseases; BODY mass index; TOXICOLOGY of fluorine; VOLUNTEERS
- Publication
Biological Trace Element Research, 2010, Vol 138, Issue 1-3, p22
- ISSN
0163-4984
- Publication type
Article
- DOI
10.1007/s12011-009-8595-3