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- Title
Selectarea și utilizarea raţională a preparatelor enzimatice pancreatice.
- Authors
Bacinschi, Nicolae; Guțul, Anastasia; Cebotari, Laura; Mihalachi-Anghel, Maria
- Abstract
Exocrine insufficiency of the pancreas, caused by a wide range of diseases and pathological conditions of the pancreas, stomach, intestines, liver and biliary system, as well as some functional conditions, is reduced to disorders of digestion, absorption and nutrition and requires careful evaluation for developing appropriate treatment strategies. Fluctuations in the arsenal of pancreatic enzyme replacement drugs on the market are due to insufficient and inadequate response determined by the composition, dosage form, activity of enzymes and dosing regimens. Experimental and clinical studies are devoted to: obtain enzymatic drugs of vegetal, bacterial, fungal and synthetic origin; new drug forms (minimicrospheres, nanofibers); review of indications for administration; systematization and optimization of the administration way and dosing regimen; specify the particularities of management of patients with exocrine insufficiency of different etiologies. Particular attention should be paid to improving the knowledge of practicing physicians in the field of enzyme replacement therapy and educating patients with exocrine insufficiency of the pancreas. The complex approach to the problems of pancreatic pathology will allow the accomplishement of a rational and personalized therapy
- Subjects
ENZYME replacement therapy; PANCREATIC enzymes; EXOCRINE pancreatic insufficiency; DRUG marketing; STOMACH; PANCREAS; GALLBLADDER
- Publication
Farmacist.ro, 2022, Issue 2, p16
- ISSN
1584-6539
- Publication type
Article