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- Title
Maternal Behçet Hastalığının Fetal Adrenal Bez Boyutlarına Etkisi.
- Authors
HENDEM, DERYA UYAN; ŞAHİN, DİLEK
- Abstract
Aim: We aimed to investigate fetal adrenal gland sizes in pregnancies with maternal Behçet's Disease (BD). hypothesizing that increased inflammation in pregnancies complicated with maternal BD may cause premature maturation of the fetal adrenal gland, and therefore fetal adrenal gland size may change. Materials and Methods: This cross-sectional study was carried out between May 2022 and May 2023 in Ankara City Hospital perinatology clinic. Twenty-one pregnant women with BD at 31-34 weeks of gestation and 63 randomly selected healthy pregnant women whose gestational age were matched with the case group were included in the study. Transverse adrenal area (TAA), transverse fetal zone area (FZA) and the ratio of fetal zone area to transverse adrenal area (FZA/TAA) were calculated using the formula length x width x n by measuring the width and length of the fetal zone with both adrenal glands. Fetal adrenal measurements were compared between the case and control groups, as well as in the BD subgroups with and without exacerbation. Results: Total adrenal width, TAA, fetal zone width and FZA in the left adrenal gland were significantly higher in the case group. The left FZA/TAA ratio was found to be statistically significantly higher in the case group. In the right adrenal gland, fetal zone width, FZA and FZA/TAA ratios were significantly higher in the case group. In addition, fetal zone width, FZA and FZA/TAA ratios were significantly higher in the left adrenal gland, and total adrenal length, TAA, fetal zone width and FZA were statistically significantly higher in the right adrenal gland in the exacerbated group. Conclusion: Fetal adrenal gland dimensions may be affected in pregnancies compleated by maternal BD. This effect is seen mostly in the fetal zone of the adrenal gland and is more prominent in the group who had an attack during pregnancy. Fetuses exposed to intrauterine stress due to increased inflammation and cytokine levels in BD pregnancies may have earlier maturation of the adrenal gland.
- Publication
Jinekoloji-Obstetrik & Neonatoloji Tip Dergisi, 2023, Vol 20, Issue 3, p1791
- ISSN
1304-5512
- Publication type
Article
- DOI
10.38136/jgon.1268172