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- Title
The Effect of Melatonin on the Sleep Quality of Patients at Post CUU.
- Authors
Rad, Peyman; Mohammad Zaman Kamkar; Seyede Asma Hossein Ashrafi
- Abstract
Background: Melatonin is effective in reducing insomnia, reducing the delay in going to bed, reducing the number of wakeups when asleep, and treating insomnia and sleep disorders. It is also more effective than benzodiazepine. Using this medication can be very effective in reducing the sleep length and setting the biological clock in patients. Therefore, considering theabove-mentioned points and the importance of sleep in patients with a history of illness, this study has been designed and implemented on patients suffering from sleep disorders, admitted to the Post CCU of Sayyad Shirazi Hospital. Material and Method: This study is a clinical trial performed on patients admitted to the Post CCU department of Sayyad Shirazi Hospital in the city of Gorgan, in 2017. In this study, 110 patients were enrolled. In the end, 12 patients were excluded from the study, and 98 patients were included who were examined. The samples were randomized. The samples were randomly divided into two groups and received melatonin and placebo. The first patient entered the melatonin group and received medicine, and the second one entered the placebo group and did not receive medicine. This process continued until the end of the sampling process. A checklist was also provided to complete the demographic attributes of the patients. The instrument used to determine the sleep quality of the patients was the Pittsburgh sleep quality questionnaire. Results: In each group, 30 patients (61.2%) were male and 19 patients (38.8%) were female. The mean age of the melatonin group was 55.04 ± 8.12 years, and it was 56.02 ± 7.8 years for the placebo group. In this study, the overall score of the sleep quality for the melatonin group before intervention was 14.95 ± 1.48, and the average score of that factor after intervention was 11.66 ± 1.50, being statistically significant based on the T-paired test. In the placebo group, the overall scores of the sleep quality before and after intervention were 15.48 ± 1.47 and 15.24 ± 1.71, respectively, not being statistically significant (p = 0.129). Also in the melatonin group, the score of the overall sleep quality was 11.65 ± 1.50 after intervention, being lower than that of the placebo group, i.e. 15.24 ± 1.71, based on the independent t-test (p = 0.0001). In the placebo group, the score obtained for the sleep time, sleep efficiency and sleep disturbances was significantly higher for the period after intervention than before the intervention, being statistically significant. However, in terms of the mental quality of the sleep, the score was less before intervention, being statistically significant (p = 0.000). In other subscales, the changes before and after intervention were not significant. However, the scores for the melatonin group decreased in all subscales after intervention, with all of them being statistically significant. In addition, the correlation between the effect of melatonin on the patients' sleep quality and various factors such as age, gender, reason for hospitalization, and the living place were investigated, and after evaluation, it was demonstrated that the effect of these factors on the sleep quality was not statistically significant, being unaffected by those variables. Conclusion: Based on the results of the current study, the sleep quality score of the patients admitted to CCU improved before and after 14 weeks of using melatonin compared to the placebo group, and it demonstrated a quality improvement. According to this finding, Melatonin can be used by patients suffering from sleep disorders to improve their treatment quality and life quality as a result of the improvement in their sleep quality.
- Subjects
PITTSBURGH (Pa.); MELATONIN; SLEEP; SLEEP disorders; BIOLOGICAL rhythms; URBAN hospitals
- Publication
Iranian Journal of Psychiatry & Behavioral Sciences / Progress in Psychiatry & Behavioral Sciences, 2018, p173
- ISSN
1735-8639
- Publication type
Article