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Identification of novel biomarker as citrullinated inter-alpha-trypsin inhibitor heavy chain 4, specifically increased in sera with experimental and rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2018, v. 20, n. 1, p. N.PAG, doi. 10.1186/s13075-018-1562-7
By:
- Kawaguchi, Hoshimi;
- Matsumoto, Isao;
- Osada, Atsumu;
- Kurata, Izumi;
- Ebe, Hiroshi;
- Tanaka, Yuki;
- Inoue, Asuka;
- Umeda, Naoto;
- Kondo, Yuya;
- Tsuboi, Hiroto;
- Shinkai, Yasuhiro;
- Kumagai, Yoshito;
- Ishigami, Akihito;
- Sumida, Takayuki
Publication type:
Article
A case of otitis media with ANCA-associated vasculitis accompanied with pituitary mass successfully treated by corticosteroids.
Published in:
2018
By:
- Takahashi, Hidenori;
- Tsuboi, Hiroto;
- Umeda, Naoto;
- Toko, Hirofumi;
- Honda, Fumika;
- Ohyama, Ayako;
- Abe, Saori;
- Yokosawa, Masahiro;
- Asashima, Hiromitsu;
- Hagiwara, Shinya;
- Kondo, Yuya;
- Matsumoto, Isao;
- Hirose, Yuki;
- Hara, Akira;
- Sumida, Takayuki
Publication type:
Case Study
TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression.
Published in:
Scientific Reports, 2016, p. 38684, doi. 10.1038/srep38684
By:
- Inoue, Asuka;
- Matsumoto, Isao;
- Tanaka, Yuki;
- Umeda, Naoto;
- Takai, Chinatsu;
- Kawaguchi, Hoshimi;
- Ebe, Hiroshi;
- Yoshida, Hiroto;
- Matsumoto, Yoshihiro;
- Segawa, Seiji;
- Takahashi, Satoru;
- Sumida, Takayuki
Publication type:
Article
Subclinical inflammation with tocilizumab treatment of rheumatoid arthritis: MRI evaluation for 2 years.
Published in:
International Journal of Rheumatic Diseases, 2015, v. 18, n. 1, p. 108, doi. 10.1111/1756-185X.12460
By:
- Suzuki, Takeshi;
- Hirota, Tomoya;
- Ogishima, Hiroshi;
- Umeda, Naoto;
- Kondo, Yuya;
- Yokosawa, Masahiro;
- Miki, Haruka;
- Tsuboi, Hiroto;
- Matsumoto, Isao;
- Sumida, Takayuki
Publication type:
Article
Prevalence of soluble peptidylarginine deiminase 4 (PAD4) and anti-PAD4 antibodies in autoimmune diseases.
Published in:
Clinical Rheumatology, 2016, v. 35, n. 5, p. 1181, doi. 10.1007/s10067-015-3082-z
By:
- Umeda, Naoto;
- Matsumoto, Isao;
- Kawaguchi, Hoshimi;
- Kurashima, Yuko;
- Kondo, Yuya;
- Tsuboi, Hiroto;
- Ogishima, Hiroshi;
- Suzuki, Takeshi;
- Kagami, Yayoi;
- Sakyu, Takuya;
- Ishigami, Akihito;
- Maruyama, Naoki;
- Sumida, Takayuki
Publication type:
Article
A case of relapsing neurosarcoidosis with brain nodules and hydrocephalus successfully treated by corticosteroid and methotrexate.
Published in:
2015
By:
- Izumi Kurata;
- Hiroto Tsuboi;
- Hidenori Takahashi;
- Mizuki Yagishita;
- Saori Abe;
- Hiroshi Ebe;
- Hiroyuki Takahashi;
- Hiromitsu Asashima;
- Tomoya Hirota;
- Shinya Hagiwara;
- Naoto Umeda;
- Yuya Kondo;
- Hiroshi Ogishima;
- Takeshi Suzuki;
- Isao Matsumoto;
- Takayuki Sumida
Publication type:
Case Study
Clinical vignette.
Published in:
2015
By:
- Hiroyuki Takahashi;
- Hiroto Tsuboi;
- Hiroshi Ogishima;
- Masahiro Yokosawa;
- Hidenori Takahashi;
- Mizuki Yagishita;
- Saori Abe;
- Shinya Hagiwara;
- Hiromitsu Asashima;
- Tomoya Hirota;
- Naoto Umeda;
- Yuya Kondo;
- Takeshi Suzuki;
- Isao Matsumoto;
- Takayuki Sumida
Publication type:
Case Study
Involvement of CD161+ Vδ1+ γδ T cells in systemic sclerosis: association with interstitial pneumonia.
Published in:
2014
By:
- Segawa, Seiji;
- Goto, Daisuke;
- Horikoshi, Masanobu;
- Kondo, Yuya;
- Umeda, Naoto;
- Hagiwara, Shinnya;
- Yokosawa, Masahiro;
- Hirota, Tomoya;
- Miki, Haruka;
- Tsuboi, Hiroto;
- Ogishima, Hiroshi;
- Suzuki, Takeshi;
- Matsumoto, Isao;
- Sumida, Takayuki
Publication type:
Journal Article
Involvement of CD161+ Vδ1+ γδ T cells in systemic sclerosis: association with interstitial pneumonia.
Published in:
Rheumatology, 2014, v. 53, n. 12, p. 2259, doi. 10.1093/rheumatology/keu246
By:
- Segawa, Seiji;
- Goto, Daisuke;
- Horikoshi, Masanobu;
- Kondo, Yuya;
- Umeda, Naoto;
- Hagiwara, Shinnya;
- Yokosawa, Masahiro;
- Hirota, Tomoya;
- Miki, Haruka;
- Tsuboi, Hiroto;
- Ogishima, Hiroshi;
- Suzuki, Takeshi;
- Matsumoto, Isao;
- Sumida, Takayuki
Publication type:
Article
CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis.
Published in:
Nature Communications, 2015, v. 6, n. 9, p. 8483, doi. 10.1038/ncomms9483
By:
- Murayama, Masanori A.;
- Kakuta, Shigeru;
- Inoue, Asuka;
- Umeda, Naoto;
- Yonezawa, Tomo;
- Maruhashi, Takumi;
- Tateishi, Koichiro;
- Ishigame, Harumichi;
- Yabe, Rikio;
- Ikeda, Satoshi;
- Seno, Akimasa;
- Chi, Hsi-Hua;
- Hashiguchi, Yuriko;
- Kurata, Riho;
- Tada, Takuya;
- Kubo, Sachiko;
- Sato, Nozomi;
- Liu, Yang;
- Hattori, Masahira;
- Saijo, Shinobu
Publication type:
Article
Cutoff Values of Serum IgG4 and Histopathological IgG4+ Plasma Cells for Diagnosis of Patients with IgG4-Related Disease.
Published in:
International Journal of Rheumatology, 2012, p. 1, doi. 10.1155/2012/580814
By:
- Masaki, Yasufumi;
- Kurose, Nozomu;
- Yamamoto, Motohisa;
- Takahashi, Hiroki;
- Saeki, Takako;
- Azumi, Atsushi;
- Nakada, Shinji;
- Matsui, Shoko;
- Origuchi, Tomoki;
- Nishiyama, Susumu;
- Yamada, Kazunori;
- Kawano, Mitsuhiro;
- Hirabayashi, Akira;
- Fujikawa, Keita;
- Sugiura, Tomoko;
- Horikoshi, Masanobu;
- Umeda, Naoto;
- Minato, Hiroshi;
- Nakamura, Takuji;
- Iwao, Haruka
Publication type:
Article
Peptidyl arginine deiminase inhibition suppresses arthritis via decreased protein citrullination in joints and serum with the downregulation of interleukin-6.
Published in:
Modern Rheumatology, 2019, v. 29, n. 6, p. 964, doi. 10.1080/14397595.2018.1532545
By:
- Hoshimi Kawaguchi;
- Isao Matsumoto;
- Atsumu Osada;
- Izumi Kurata;
- Hiroshi Ebe;
- Yuki Tanaka;
- Asuka Inoue;
- Naoto Umeda;
- Yuya Kondo;
- Hiroto Tsuboi;
- Akihito Ishigami;
- Takayuki Sumida
Publication type:
Article
Anti-cyclic citrullinated glucose-6-phosphate isomerase peptide-7 (CCG-7) antibodies were suppressed by biologics treatment and deposited to citrullinated proteins in CD68-positive cells in the RA synovium.
Published in:
Modern Rheumatology, 2017, v. 27, n. 5, p. 914, doi. 10.1080/14397595.2016.1270388
By:
- Naoto Umeda;
- Isao Matsumoto;
- Yuki Tanaka;
- Hoshimi Kawaguchi;
- Hiroshi Ebe;
- Yayoi Kagami;
- Akihito Ishigami;
- Takayuki Sumida
Publication type:
Article
Effectiveness of abatacept for patients with Sjögren's syndrome associated with rheumatoid arthritis. An open label, multicenter, one-year, prospective study: ROSE (Rheumatoid Arthritis with Orencia Trial toward Sjögren's syndrome Endocrinopathy) trial
Published in:
Modern Rheumatology, 2016, v. 26, n. 6, p. 891, doi. 10.3109/14397595.2016.1158773
By:
- Hiroto Tsuboi;
- Isao Matsumoto;
- Shinya Hagiwara;
- Tomoya Hirota;
- Hiroyuki Takahashi;
- Hiroshi Ebe;
- Masahiro Yokosawa;
- Mizuki Yagishita;
- Hidenori Takahashi;
- Izumi Kurata;
- Ayako Ohyama;
- Fumika Honda;
- Hiromitsu Asashima;
- Haruka Miki;
- Naoto Umeda;
- Yuya Kondo;
- Shintaro Hirata;
- Kazuyoshi Saito;
- Yoshiya Tanaka;
- Yoshiro Horai
Publication type:
Article
Association of anti-Ro/SSA antibody with response to biologics in patients with rheumatoid arthritis.
Published in:
Modern Rheumatology, 2016, v. 26, n. 6, p. 857, doi. 10.3109/14397595.2016.1153567
By:
- Shinya Hagiwara;
- Hiroto Tsuboi;
- Fumika Honda;
- Hidenori Takahashi;
- Izumi Kurata;
- Ayako Ohyama;
- Mizuki Yagishita;
- Saori Abe;
- Yuko Kurashima;
- Syunta Kaneko;
- Hoshimi Kawaguchi;
- Hiroyuki Takahashi;
- Hiroshi Ebe;
- Masahiro Yokosawa;
- Hiromitsu Asashima;
- Tomoya Hirota;
- Naoto Umeda;
- Yuya Kondo;
- Isao Matsumoto;
- Takayuki Sumida
Publication type:
Article
Evaluation of changes in magnetic resonance images following 24 and 52 weeks of treatment of rheumatoid arthritis with infliximab, tocilizumab, or abatacept.
Published in:
Modern Rheumatology, 2016, v. 26, n. 1, p. 29, doi. 10.3109/14397595.2015.1069471
By:
- Tomoya Hirota;
- Takeshi Suzuki;
- Hiroshi Ogishima;
- Shinya Hagiwara;
- Hiroshi Ebe;
- Hiroyuki Takahashi;
- Masahiro Yokosawa;
- Naoto Umeda;
- Yuya Kondo;
- Hiroto Tsuboi;
- Isao Matsumoto;
- Takayuki Sumida
Publication type:
Article
Efficacy and safety of abatacept for patients with Sjögren's syndrome associated with rheumatoid arthritis: Rheumatoid Arthritis with Orencia Trial toward Sjögren's syndrome Endocrinopathy (ROSE) trial-an open-label, one-year, prospective study-Interim analysis of 32 patients for 24 weeks
Published in:
Modern Rheumatology, 2015, v. 25, n. 2, p. 187, doi. 10.3109/14397595.2014.951144
By:
- Tsuboi, Hiroto;
- Matsumoto, Isao;
- Hagiwara, Shinya;
- Hirota, Tomoya;
- Takahashi, Hiroyuki;
- Ebe, Hiroshi;
- Yokosawa, Masahiro;
- Hagiya, Chihiro;
- Asashima, Hiromitsu;
- Takai, Chinatsu;
- Miki, Haruka;
- Umeda, Naoto;
- Kondo, Yuya;
- Ogishima, Hiroshi;
- Suzuki, Takeshi;
- Hirata, Shintaro;
- Saito, Kazuyoshi;
- Tanaka, Yoshiya;
- Horai, Yoshiro;
- Nakamura, Hideki
Publication type:
Article
Clinical features of patients with IgG4-related disease complicated with perivascular lesions.
Published in:
Modern Rheumatology, 2015, v. 25, n. 1, p. 105, doi. 10.3109/14397595.2014.903596
By:
- Ebe, Hiroshi;
- Tsuboi, Hiroto;
- Hagiya, Chihiro;
- Takahashi, Hiroyuki;
- Yokosawa, Masahiro;
- Hagiwara, Shinya;
- Hirota, Tomoya;
- Kurashima, Yuko;
- Takai, Chinatsu;
- Miki, Haruka;
- Asashima, Hiromitsu;
- Umeda, Naoto;
- Kondo, Yuya;
- Ogishima, Hiroshi;
- Suzuki, Takeshi;
- Chino, Yusuke;
- Matsumoto, Isao;
- Sumida, Takayuki
Publication type:
Article
Clinicopathological features of IgG4-related disease complicated with orbital involvement.
Published in:
Modern Rheumatology, 2014, v. 24, n. 3, p. 471, doi. 10.3109/14397595.2013.844307
By:
- Hagiya, Chihiro;
- Tsuboi, Hiroto;
- Yokosawa, Masahiro;
- Hagiwara, Shinya;
- Hirota, Tomoya;
- Takai, Chinatsu;
- Asashima, Hiromitsu;
- Miki, Haruka;
- Umeda, Naoto;
- Horikoshi, Masanobu;
- Kondo, Yuya;
- Sugihara, Makoto;
- Ogishima, Hiroshi;
- Suzuki, Takeshi;
- Hiraoka, Takahiro;
- Kaji, Yuichi;
- Matsumoto, Isao;
- Oshika, Tetsuro;
- Sumida, Takayuki
Publication type:
Article
Analysis of subclinical synovitis detected by ultrasonography and low-field magnetic resonance imaging in patients with rheumatoid arthritis.
Published in:
Modern Rheumatology, 2014, v. 24, n. 1, p. 60, doi. 10.3109/14397595.2013.854050
By:
- Ogishima, Hiroshi;
- Tsuboi, Hiroto;
- Umeda, Naoto;
- Horikoshi, Masanobu;
- Kondo, Yuya;
- Sugihara, Makoto;
- Suzuki, Takeshi;
- Matsumoto, Isao;
- Sumida, Takayuki
Publication type:
Article
Therapeutic efficacy of tocilizumab in patients with rheumatoid arthritis refractory to anti-tumor-necrosis-factor inhibitors: 1 year follow-up with low-field extremity MRI.
Published in:
Modern Rheumatology, 2013, v. 23, n. 4, p. 782, doi. 10.3109/s10165-012-0746-2
By:
- Suzuki, Takeshi;
- Horikoshi, Masanobu;
- Sugihara, Makoto;
- Hirota, Tomoya;
- Ogishima, Hiroshi;
- Umeda, Naoto;
- Kondo, Yuya;
- Tsuboi, Hiroto;
- Hayashi, Taichi;
- Chino, Yusuke;
- Matsumoto, Isao;
- Sumida, Takayuki
Publication type:
Article
Six-transmembrane epithelial antigen of prostate4 (STEAP4) is a tumor necrosis factor alpha-induced protein that regulates IL-6, IL-8, and cell proliferation in synovium from patients with rheumatoid arthritis.
Published in:
Modern Rheumatology, 2012, v. 22, n. 1, p. 128, doi. 10.3109/s10165-011-0475-y
By:
- Tanaka, Yoko;
- Matsumoto, Isao;
- Iwanami, Keiichi;
- Inoue, Asuka;
- Minami, Reiko;
- Umeda, Naoto;
- Kanamori, Akihiro;
- Ochiai, Naoyuki;
- Miyazawa, Keiji;
- Sugihara, Makoto;
- Hayashi, Taichi;
- Goto, Daisuke;
- Ito, Satoshi;
- Sumida, Takayuki
Publication type:
Article
Comparative suppressive effects of tyrosine kinase inhibitors imatinib and nilotinib in models of autoimmune arthritis.
Published in:
Modern Rheumatology, 2011, v. 21, n. 3, p. 267, doi. 10.3109/s10165-010-0392-5
By:
- Akashi, Naotsugu;
- Matsumoto, Isao;
- Tanaka, Yoko;
- Inoue, Asuka;
- Yamamoto, Kayo;
- Umeda, Naoto;
- Tanaka, Yuki;
- Hayashi, Taichi;
- Goto, Daisuke;
- Ito, Satoshi;
- Sekiguchi, Kaneo;
- Sumida, Takayuki
Publication type:
Article
Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show a reduced or insufficient response to infliximab.
Published in:
Modern Rheumatology, 2009, v. 19, n. 3, p. 229, doi. 10.3109/s10165-009-0162-4
By:
- Horikoshi, Masanobu;
- Ito, Satoshi;
- Ishikawa, Mizue;
- Umeda, Naoto;
- Kondo, Yuya;
- Tsuboi, Hiroto;
- Hayashi, Taichi;
- Goto, Daisuke;
- Matsumoto, Isao;
- Sumida, Takayuki
Publication type:
Article

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