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- Title
Contact allergy to fragrances: current patch test results (2005-2008) from the Information Network of Departments of Dermatology.
- Authors
Uter, Wolfgang; Geier, Johannes; Frosch, Peter; Schnuch, Axel
- Abstract
Background: Contact sensitization to fragrances is common both in clinical and in population samples. The spectrum of allergens is broad and diverse, and to some extent covered by a set of screening agents. Objectives: To examine the current frequency of contact sensitization to fragrance allergens in patients routinely patch tested for suspected allergic contact dermatitis with the baseline series and special series. Patients and methods: Between 2005 and 2008, 40 709 patients were patch tested in the departments of the Information Network of Departments of Dermatology ( ). Results with selected fragrances were analysed. Results: Of all patients tested with the German baseline series, 15.1% reacted positively to fragrance mix (FM) I (6.6% positive), FM II (4.6% positive) or Myroxylon pereirae resin (balsam of Peru, 6.8% positive). Among the single constituents of FM I, Evernia prunastri [oak moss absolute (abs.)] was the leading allergen, and amyl cinnamal the least frequent allergen. Among fragrances not included in FM I or FM II, Evernia furfuracea (tree moss abs.) was the most common allergen. Conclusions: For diagnostic purposes, it is necessary to combine several screening agents. The frequency of contact sensitization differs greatly between single fragrances.
- Subjects
DERMATOLOGY; ALLERGENS; SKIN diseases; ODORS; SKIN inflammation; MYROXYLON peruiferum
- Publication
Contact Dermatitis (01051873), 2010, Vol 63, Issue 5, p254
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/j.1600-0536.2010.01759.x