We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
SUBCUTANEOUS PHAEOHYPHOMYCOSIS CAUSED BY STERILE CHAETOMIUM SPP. IN IRAN.
- Authors
Najafzadeh, Mohammad Javad; Keisari, Maryam Saradeghi; Farahyar, Shirin; Ganjbakhsh, Majid; Ziaee, Masood; Naseri, Ali NaseriAli; Berenji, Fariba; De Hoog, Sybren G.; Fata, Abdolmajid
- Abstract
We report a case of a 66-year-old Iranian woman with phaeohyphomycosis, there was a mass (approximately 1×1 cm in size) on the right lateral of neck. She had dysphagia, hoarseness and no pain. She complains about black discharge, irritation, headache, obscurity and periodical vertigo. Histological examination of biopsy fragments from the lesions showed septate branched, dematiaceous, hyphae. Direct microscopy of mass in 20% potassium hydroxide (KOH) and Histological examination showed septate light brown hyphae. Sporulation of the fungus isolated from the patient was unsuccessful in a 1-months culture on SDA, MEA, PDA, water agar with paper sterile filter and plant steam agar. In slide culture we just find sterile mycelia. Based on molecular identification, Chaetomium spp was confirmed by sequencing of the ITS (Internal Transcribed Spacer) domain of the rDNA gene and comparison with sequences held at gene bank and the Centraalbureau voor Schimmelcultures (CBS). ITS sequencing show that the isolate clustered within the ascomycete genus Chaetomium. The sequence did not fully match with any sequences of available ex-type strains of Chaetomium, Thielavia and Papulaspora and hence might belong to an undescribed species. After local excision of the mass and Antifungal therapy by ketoconazole (200 mg twice a day), the lesion healed completely.
- Subjects
IRAN; CHAETOMIUM; DEGLUTITION disorders; COMMUNICABLE disease treatment; MYCOSES; HEADACHE; FUNGAL spores; POTASSIUM hydroxide; KETOCONAZOLE
- Publication
Jundishapur Journal of Microbiology, 2013, p52
- ISSN
2008-3645
- Publication type
Case Study