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- Title
Analysis of Pilus Biogenesis Genes in Bacteria Expressing Type IV Pili.
- Authors
AHMED, Saeed; AHMAD, Ijaz; AHMAD, Shakoor; SHAH, Zahir; SHAH, Muqadar; KHAN, Farhan Anwar
- Abstract
The structural and sequences similarities of type-IV pili proteins were analysed in Pseudomonas aeruginosa, Vibrio cholerae, Neisseria meningitidis and Neisseria gonorrhoeae. Pathogenic Neisseria species possess pili-genes that code structural and assembly proteins of type- IV pili. A collection of assembly proteins reveal homology amongst P. aeruginosa and Neisseria. While in V. cholerae, these proteins ensure functional counterparts. The pilus retraction and assembly ATPases, PilB/PilF and PilT, PilU are homologous in Neisseria and P. aeruginosa, whereas V. cholerae holds only one ATPase called TcpT. In this work only type-IV pilus machinery of P. aeruginosa shows high likeness with pathogenic Neisseria.
- Subjects
PSEUDOMONAS aeruginosa; MICROBIAL virulence; NEISSERIA gonorrhoeae; ADENOSINE triphosphatase; VIBRIO cholerae
- Publication
Kafkas Universitesi Veteriner Fakultesi Dergisi, 2019, Vol 25, Issue 1, p125
- ISSN
1300-6045
- Publication type
Article
- DOI
10.9775/kvfd.2018.19910