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- Title
Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study.
- Authors
Soto, Caitlin L; Hsu, Alice J; Lee, Jae Hyoung; Dzintars, Kathryn; Choudhury, Rebecca; Jenkins, Timothy C; McCreary, Erin K; Quartuccio, Katelyn S; Stohs, Erica J; Zimmerman, Matty; Tamma, Pranita D
- Abstract
In a propensity-score-weighted cohort of 183 adults with carbapenem-resistant Enterobacterales bacteremia at 24 US hospitals, patients receiving short courses of active therapy (7–10 days, median 9 days) experienced similar odds of recurrent bacteremia or death within 30 days as those receiving prolonged courses of active therapy (14–21 days, median 14 days).
- Subjects
UNITED States; MORTALITY risk factors; ANTIBIOTICS; BACTEREMIA; RESEARCH; SCIENTIFIC observation; CARBAPENEM-resistant bacteria; ENTEROBACTERIACEAE diseases; TREATMENT duration; DISEASE relapse; RISK assessment; TREATMENT effectiveness; DESCRIPTIVE statistics; LONGITUDINAL method; DISEASE risk factors; EVALUATION
- Publication
Clinical Infectious Diseases, 2024, Vol 78, Issue 1, p27
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciad476