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- Title
Calcifying Odontogenic Cyst Associated With Dentigerous Cyst in a 15-Year-Old Girl.
- Authors
Aristizabal Arboleda, Paola; Sánchez-Romero, Celeste; de Almeida, Oslei Paes; Flores Alvarado, Sergio A.; Martínez Pedraza, Ricardo
- Abstract
Calcifying odontogenic cyst (COC) is a rare odontogenic cyst with ameloblastic epithelial lining containing clusters of ghost cells. COCs have been described in association with several odontogenic tumors, more commonly odontomas and rarely with dentigerous cyst (DC). In this article, we describe a case of COC associated with DC in a 15-year-old girl, who presented with a swelling on the right middle third of the face, producing facial asymmetry. Panoramic radiography showed a well-circumscribed, corticated, and unilocular radiolucency at the level of the right maxillary sinus, involving 2 unerupted premolars. The lesion was enucleated and histologically revealed a COC associated with DC, which presented mucous metaplasia. Immunohistochemical reactions were performed to better illustrate this rare synchronous occurrence of COC and DC, showing positivity for CK5, CK14, CK19, and p63 in both lesions. CK18 was negative in COC, and Bcl-2 was negative in DC. Periodic acid Schiff highlighted the mucous cells in the DC lining.
- Subjects
DENTIGEROUS cyst; GIRLS' health; EPITHELIAL cells; PANORAMIC radiography; IMMUNOHISTOCHEMISTRY
- Publication
International Journal of Surgical Pathology, 2018, Vol 26, Issue 8, p758
- ISSN
1066-8969
- Publication type
Article
- DOI
10.1177/1066896918777639