We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Accumulated hypertension burden on atrial fibrillation risk in diabetes mellitus: a nationwide population study.
- Authors
Choi, JungMin; Lee, So‑Ryoung; Choi, Eue‑Keun; Lee, HuiJin; Han, MinJu; Ahn, Hyo-Jeong; Kwon, Soonil; Lee, Seung-Woo; Han, Kyung‑Do; Oh, Seil; Lip, Gregory Y. H.
- Abstract
Background: Patients with diabetes mellitus have an increased risk of incident atrial fibrillation (AF). The effect of accumulated hypertension burden is a less well-known modifiable risk factor. We explored the relationship between accumulated hypertension burden and incident AF in these patients. Methods: We evaluated data for 526,384 patients with diabetes who underwent three consecutive health examinations, between 2009 and 2012, from the Korean National Health Insurance Service. Hypertension burden was calculated by assigning points to each stage of hypertension in each health examination: 1 for stage 1 hypertension (systolic blood pressure [SBP] 130–139 mmHg; diastolic blood pressure [DBP] 80–89 mmHg); 2 for stage 2 (SBP 140–159 mmHg and DBP 90–99 mmHg); and 3 for stage 3 (SBP ≥ 160 mmHg or DBP ≥ 100 mmHg). Patients were categorized into 10 hypertensive burden groups (0–9). Groups 1–9 were then clustered into 1–3, 4–6, and 7–9. Results: During a mean follow-up duration of 6.7 ± 1.7 years, AF was newly diagnosed in 18,561 (3.5%) patients. Compared to patients with hypertension burden 0, those with burden 1 to 9 showed a progressively increasing risk of incident AF: 6%, 11%, 16%, 24%, 28%, 41%, 46%, 57%, and 67% respectively. Clusters 1–3, 4–6, and 7–9 showed increased risks by 10%, 26%, and 45%, respectively, when compared to a hypertension burden of 0. Conclusions: Accumulated hypertension burden was associated with an increased risk of incident AF in patients with diabetes. Strict BP control should be emphasized for these patients.
- Subjects
ATRIAL fibrillation; DIABETES; DIASTOLIC blood pressure; SYSTOLIC blood pressure; NATIONAL health insurance
- Publication
Cardiovascular Diabetology, 2023, Vol 22, Issue 1, p1
- ISSN
1475-2840
- Publication type
Article
- DOI
10.1186/s12933-023-01736-4