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- Title
Dendritic Cells.
- Authors
BANCHEREAU, JACQUES; PACZESNY, SOPHIE; BLANCO, PATRICK; BENNETT, LYNDA; PASCUAL, VIRGINIA; FAY, JOSEPH; PALUCKA, A. KAROLINA
- Abstract
A bstract: The immune system is controlled by dendritic cells (DCs). Just as lymphocytes comprise different subsets, DCs comprise several subsets that differentially control lymphocyte function. In humans, the myeloid pathway includes Langerhans cells (LCs) and interstitial DCs (intDCs). While both subsets produce IL-12, only intDCs make IL-10 and induce B cell differentiation. Another pathway includes plasmacytoid DCs, which promptly secrete large amounts of IFN-α/β viral encounter. Thus, insights into in vivo DC functions are important to understand the launching and modulation of immunity.
- Publication
Annals of the New York Academy of Sciences, 2003, Vol 987, Issue 1, p180
- ISSN
0077-8923
- Publication type
Article
- DOI
10.1111/j.1749-6632.2003.tb06047.x