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- Title
Rational design of EDTA-incorporated nanoflowers as novel and effective endodontic disinfection against biofilms.
- Authors
Aslan, Tugrul; Dadi, Şeyma; Kafdag, Ozgur; Temur, Nimet; Ildiz, Nilay; Ocsoy, Ismail; Ustun, Yakup
- Abstract
The ethylenediaminetetradiacetic acid (EDTA) is one of the most commonly used irrigation solutions. Although EDTA has a very low antimicrobial property, it is used to remove inorganic part of smear layer in areas of root canal system. Herein, we developed EDTA-incorporated nanoflowers (EDTA NFs), for the first time, as novel and effective irrigation solution with quite high antimicrobial property to provide complete disinfection in root canal system. We both systematically elucidated the formation of the EDTA NFs with various techniques, and their catalytic and antimicrobial activities in the presence of hydrogen peroxide (H2O2) were documented through intrinsic EDTA property and peroxidase-like activities.
- Subjects
ENDODONTICS; DENTAL pulp cavities; BIOFILMS; HYDROGEN peroxide; CATALYTIC activity
- Publication
Odontology, 2024, Vol 112, Issue 2, p444
- ISSN
1618-1247
- Publication type
Article
- DOI
10.1007/s10266-023-00857-2