We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Complete genome sequence and analysis of a new lethal arterivirus, Trionyx sinensis hemorrhagic syndrome virus (TSHSV), amplified from an infected Chinese softshell turtle.
- Authors
Lyu, Sunjian; Yuan, Xuemei; Zhang, Haiqi; Shi, Weida; Hang, Xiaoying; Liu, Li; Cao, Zheng; Wu, Yinglei
- Abstract
Trionyx sinensis hemorrhagic syndrome virus (TSHSV) is a newly discovered lethal arterivirus that causes serious disease in Trionyx sinensis in China. In this study, the complete genome sequence of TSHSV was determined by RACE cloning, and the functions of the predicted proteins were predicted. The complete genome of TSHSV was found to be 17,875 bp in length, and a 3'-end poly(A) tail was detected. Eight TSHSV hypothetical proteins (TSHSV-HPs) were predicted by gene model identification. TSHSV-HP2, 3 and 4 were associated with replicase activity, since papain-like protease (PLPs), serine-type endopeptidase, P-loop-containing nucleoside triphosphate hydrolase, and EndoU-like endoribonuclease motifs were detected. Phylogenetic analysis showed that TSHSV clusters with an arterivirus from a Chinese broad-headed pond turtle.
- Subjects
CHINA; SOFT-shelled turtles; NUCLEOTIDE sequencing; SEQUENCE analysis; EMYDIDAE; SYNDROMES; LOGGERHEAD turtle; HYDROLASES
- Publication
Archives of Virology, 2019, Vol 164, Issue 10, p2593
- ISSN
0304-8608
- Publication type
Article
- DOI
10.1007/s00705-019-04324-8