We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Ischemia-Modified Albumin and Antioxidant Protection in Newborns with Asphyxia of Varying Severity.
- Authors
Delsuz, S. F.; Shalina, R. I.; Karaganova, E. Ya.; Kurtser, M. A.; Babenkova, I. V.; Teselkin, Yu. O.; Osipov, A. N.; Vladimirov, Yu. A.
- Abstract
The content of ischemia-modified albumin (IMA), serum albumin, and antioxidant capacity of blood serum was studied in healthy newborns and in newborns with moderate and severe asphyxia on days 1-2 and 3-4 of the postnatal period. Changes in these indicators were found in both groups of newborns with birth asphyxia in comparison with the group of healthy newborns and were more pronounced in children with severe asphyxia. An increase in the IMA level (by 1.6 times; p<0.001) and antioxidant capacity of blood serum (by 2.4 times; p<0.001) and a decrease in serum albumin content (by 1.5 times; p<0.001) were found in severe asphyxia on days 1-2. Analysis of changes in these indicators by days 3-4 allows to talk about a decrease in the intensity of free-radical reactions in newborns with birth asphyxia during complex therapy.
- Publication
Bulletin of Experimental Biology & Medicine, 2023, Vol 175, Issue 5, p620
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-023-05913-z