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- Title
Vasodilator Nerve Fibres to the Submaxillary Gland of the Cat.
- Authors
KARPINSKI, E.; BARTON, S.; SCHACHTER, M.
- Abstract
IN 1851 Claude Bernard1 presented the first evidence for the existence of vasoconstrictor nerves in the cervical sympathetic nerve to the blood vessels of the rabbit's ear. In 1858 he demonstrated2 that there was a dual neurovascular regulation in the submaxillary gland of the dog by showing, that whereas electrical stimulation of the sympathetic nerve reduced the venous outflow from the gland, stimulation of the parasympathetic (chorda tympani) greatly increased it. He concluded, therefore, that there were vasodilator, as well as vasoconstrictor, nerves and that this afforded a mechanism whereby the blood flow through the gland was regulated locally, independent of alterations in systemic blood pressure. He regarded this as a further example of his principle of homeostasis.
- Publication
Nature, 1971, Vol 232, Issue 5306, p122
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/232122a0