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- Title
Dual trigger increases the number of top quality embryos in normal responders.
- Authors
Kalra, Priyanka; Devi, M. Gouri; Sharma, Meeta
- Abstract
Context: Human chorionic gonadotropin (hCG) has been used for years for oocyte maturation in IVF cycles, however, with the risk of a few complications like ovarian hyperstimulation. The introduction of gonadotropin-releasing hormone (GnRH) agonist along with hCG as a dual trigger has helped to reduce the incidence of such complications. Aims: The study aims to compare the outcomes of IVF cycles in hCG versus hCG plus GnRH (dual trigger). Settings and Design: Retrospective center-based study. Materials and Methods: Retrospective center-based study to compare the effect of hCG and dual trigger on the cycle outcomes in normal responders. Statistics: Data analysis was done using ClinCalc online calculator through chi-square test, two-independent t test. P < 0.05 was considered to indicate statistical significance. Results: The number of oocytes and clinical pregnancy rates was higher in the dual trigger group. A higher number of top quality embryos were formed in the dual trigger group with statistical significance. Conclusions: Dual trigger can help to improve the outcomes of IVF in normal responders too.
- Subjects
EMBRYOS; OVUM; RETROSPECTIVE studies; ACQUISITION of data; GONADOTROPIN releasing hormone; PREGNANCY outcomes; COMPARATIVE studies; T-test (Statistics); MEDICAL records; FERTILIZATION in vitro; DATA analysis software; CHORIONIC gonadotropins
- Publication
Fertility Science & Research, 2022, Vol 9, Issue 1, p46
- ISSN
2394-4285
- Publication type
Article
- DOI
10.4103/fsr.fsr_1_22