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- Title
Tackling reproducibility in academic preclinical drug discovery.
- Authors
Frye, Stephen V.; Arkin, Michelle R.; Arrowsmith, Cheryl H.; Conn, P. Jeffrey; Glicksman, Marcie A.; Hull-Ryde, Emily A.; Slusher, Barbara S.
- Abstract
The reproducibility of biomedical research on novel drug targets has become suspect. Here, we highlight how drug discovery centres embedded in academic institutions, but with a translational imperative, can help address this reproducibility crisis.
- Subjects
TARGETED drug delivery; MEDICAL centers; GENETIC translation; MEDICAL research; UNIVERSITIES &; colleges; ACADEMIC medical centers; ANIMALS; DRUG design; CLINICAL drug trials; RESEARCH evaluation; STANDARDS
- Publication
Nature Reviews Drug Discovery, 2015, Vol 14, Issue 11, p733
- ISSN
1474-1776
- Publication type
journal article
- DOI
10.1038/nrd4737