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- Title
Autoimmunity and HIV/simian immunodeficiency virus infection: A two edged sword.
- Authors
Ansari, Aftab A.; Pattanapanyasat, Kovit; Pereira, Lara E.
- Abstract
The purpose of this review is to provide an overview of the spectrum of autoimmune responses that we have so far characterized in the simian immunodeficiency virus (SIV)-infected disease susceptible rhesus macaques, the potential role of the lymphopenic state for the generation of the autoimmune response and the important new finding that such autoimmune response in fact can serve to provide both clinical benefit and clinical disease depending on the stage of the disease and the nature of the host proteins that are recognized during this process.
- Subjects
AUTOIMMUNITY; IMMUNITY; HIV infections; LENTIVIRUS diseases; SIMIAN viruses; IMMUNODEFICIENCY
- Publication
Hepatology Research, 2007, Vol 37, pS389
- ISSN
1386-6346
- Publication type
Article
- DOI
10.1111/j.1872-034X.2007.00225.x