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- Title
MICROBIOLOGICAL AND EXFOLIATIVE CYTOLOGICAL FINDING OF THE ORAL CANDIDA DUBLINIENSIS IN PATIENTS WHO ARE PSHYOACTIVE SUBSTANCES ADDICTS.
- Authors
Hadžić, S.; Dedić, A.; Gojkov-Vukelić, M.; Pašić, E.; Hodžić, M.; Topić, B.
- Abstract
Goal: The goal of this study was to examine the presence and frequency of Candida dubliniensis in the oral cavity in psychoactive substance addicts using methods of exfoliative cytology to determine the possibility of oral precancerous conditions. Material and methods: The research included 60 in-patients from the Institute for Alcoholism and Other Addictions of the Sarajevo Canton who were divided into two groups (alcohol addicts and substance addicts). The groups included both sexes aging 18-60. After the anamnesis, two smears were taken of the oral mucous membranes. The microbiological identification of Candida types was based on the crystallization test and cultivation on a chromatophilous basis (Chrom agar), assimilation test for yeast plants (API test), and identification test (PAL agar) for Candida dubliniensis. The second smear was taken for the exfoliative cytological test for the purpose of determining patho-histological changes. Results: Microbiological analyses have confirmed the frequency of Candida albicans (43%) and increase in the non-albicans type irrespectively of the type of addiction (34%). The presence of Candida dubliniensis has been proven in psychoactive substance addicts (23%) and it has been confirmed that the frequency of adherence of Candida dubliniensis is in proportion to the time interval of drugs addiction. The chi-quadrate test (p=0, 55297) has confirmed that there are no significant differences in cytological findings frequencies by groups. In general, bacteria are the most present group in 70, 00 % of patients irrespectively of groups. The group of alcohol addicts, metaplasia was found in 26% of patients, and in case of drug addicts, it was identified in 18% of patients. Conclusion: The statistical analysis has confirmed that psychoactive substances (drugs and alcohol) lead to an increase in oral Candida dubliniensis irrespectively of the type of addiction. In case in psychoactive substances use, the method of exfoliative cytology has demonstrated the presence of metaplasia - which constitutes a risk of oral precancerous conditions.
- Subjects
MICROBIOLOGY; EXFOLIATIVE cytology; CANDIDA; SUBSTANCE abuse; DENTAL caries; DENTAL pathology; CRYSTALLIZATION; PATIENTS
- Publication
Stomatological Review / Stomatološki Vjesnik, 2014, Vol 3, Issue 1, p43
- ISSN
0350-5499
- Publication type
Article