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- Title
Combining BRAF<sup>V</sup><sup>600E</sup> inhibition with modulators of the mitochondrial bioenergy metabolism to overcome drug resistance in metastatic melanoma.
- Authors
Livingstone, Elisabeth; Swann, Suzanne; Lilla, Carmen; Schadendorf, Dirk; Roesch, Alexander
- Abstract
The article offers the authors' views on the combination of BRAF gene inhibition with mitochondrial bioenergy metabolism modulators towards the management of drug resistant metastatic melanoma. They mention the role of its kinase in the treatment of the disease. An overview of its hypothesis is also presented.
- Subjects
BRAF genes; MELANOMA treatment; ENERGY medicine; METABOLISM; DRUG resistance in cancer cells
- Publication
Experimental Dermatology, 2015, Vol 24, Issue 9, p709
- ISSN
0906-6705
- Publication type
Article
- DOI
10.1111/exd.12718