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- Title
Observational Cohort Study of Evolving Epidemiologic, Clinical, and Virologic Features of Monkeypox in Southern France.
- Authors
Cassir, Nadim; Cardona, Florian; Tissot-Dupont, Hervé; Bruel, Christiane; Doudier, Barbara; Lahouel, Salima; Bendamardji, Karim; Boschi, Céline; Aherfi, Sarah; Edouard, Sophie; Lagier, Jean-Christophe; Colson, Philippe; Gautret, Philippe; Fournier, Pierre-Edouard; Parola, Philippe; Brouqui, Philippe; La-Scola, Bernard; Million, Matthieu
- Abstract
We enrolled 136 patients with laboratory-confirmed monkeypox during June 4-August 31, 2022, at the University Hospital Institute Méditerranée Infection in Marseille, France. The median patient age was 36 years (interquartile range 31-42 years). Of 136 patients, 125 (92%) were men who have sex with men, 15 (11%) reported previous smallpox vaccinations, and 21 (15.5%) were HIV-positive. The most frequent lesion locations were the genitals (68 patients, 53%), perianal region (65 patients, 49%), and oral/perioral area (22 patients, 17%). Lesion locations largely corresponded with the route of contamination. Most (68%) patients had isolated anal, genital, or oral lesions when they were first seen, including 56 (61%) who had >1 positive site without a visible lesion. Concurrent sexually transmitted infections were diagnosed in 19 (15%) patients, and 7 patients (5%) were asymptomatic. We recommend vaccination campaigns, intensified testing for sexually transmitted infections, and increased contact tracing to control the ongoing monkeypox outbreak.
- Subjects
EPIDEMIOLOGY of sexually transmitted diseases; LONGITUDINAL method; HOMOSEXUALITY
- Publication
Emerging Infectious Diseases, 2022, Vol 28, Issue 12, p2409
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid2812.221440