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- Title
Highly Pathogenic Reassortant Avian Influenza A(H5N1) Virus Clade 2.3.2.1a in Poultry, Bhutan.
- Authors
Marinova-Petkova, Atanaska; Franks, John; Tenzin, Sangay; Dahal, Narapati; Dukpa, Kinzang; Dorjee, Jambay; Feeroz, Mohammed M.; Rehg, Jerold E.; Barman, Subrata; Krauss, Scott; McKenzie, Pamela; Webby, Richard J.; Webster, Robert G.
- Abstract
Highly pathogenic avian influenza A(H5N1), clade 2.3.2.1a, with an H9-like polymerase basic protein 1 gene, isolated in Bhutan in 2012, replicated faster in vitro than its H5N1 parental genotype and was transmitted more efficiently in a chicken model. These properties likely help limit/eradicate outbreaks, combined with strict control measures.
- Subjects
BHUTAN; AVIAN influenza epidemiology; AVIAN influenza; ISOLATION of biotechnological microorganisms; AVIAN influenza A virus; VIRAL genetics; INFECTIOUS disease transmission; INFLUENZA epidemiology; ANIMAL experimentation; COMPARATIVE studies; EPIDEMICS; BIOLOGICAL evolution; RESEARCH methodology; MEDICAL cooperation; POULTRY; RESEARCH; RESEARCH funding; VIRUSES; EVALUATION research; RELATIVE medical risk; INFLUENZA A virus, H5N1 subtype; GENOTYPES
- Publication
Emerging Infectious Diseases, 2016, Vol 22, Issue 12, p2137
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2212.160611