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- Title
Anesthetic Potential of Herbal Plants.
- Authors
Sontakke, Rupali; Singhal, Rohit; Jain, Neetesh Kumar
- Abstract
Medicinal plants and herbs have been used since ancient times for relieving pain caused by disease, injury and surgery, some of them contributed to the development of modern anesthesia. Herbs show anesthetic activity due to presence of phytochemicals like phenols, linolool, terepenoidal principles etc. Chewing Piper betel (Piperaceae) leaves, are known to numb the mouth and dull the taste. The plain extracts from betel leaves showed both infiltration and surface anesthetic effects that were almost comparable to those of lidocaine. Spilanthes acmella (Asteraceae), is anherb growing throughout the tropics, is used for rheumatism, sore throat and toothache. Eating these leaves and flowers is known to cause numbnessto the tongue. Injections of 10% and 20% extracts produced 70% and 87% local anesthesia, respectively, while 2% lidocaine showed 97% local anesthesia. Fenchone a variety of monoterpenoids have been suggested to modulate the activity of voltage- and ligand-gated ion channel. Clove oil has been used for centuries to relieve toothaches and now studies show that it’s basically as effective as benzocaine for topically numbing pain. Capsaicin is the chemical in peppers that makes them hot but when used topically, it causes body to release a chemical called Substance P. This is the chemical that carries pain messages from the nerves to the brain. In addition to capsaicin, cayenne also contains salicylates, the same compounds found in aspirin. These are some of the herbal plants having the anesthetic potential, there are more variety of plants yet to be discovered with the same potential. Herbal anesthesia can open a new path for minor surgeries to be done with minimal adverse effects.
- Subjects
VOLTAGE-gated ion channels; LIGAND-gated ion channels; LOCAL anesthesia; CAPSAICINOIDS; MEDICINAL plants; PHYTOCHEMICALS; CULTIVARS; HERBAL medicine
- Publication
International Journal of Pharmacy & Life Sciences, 2020, Vol 11, Issue 7, p69
- ISSN
0976-7126
- Publication type
Article