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- Title
Perinatal Factors Associated with Autism Spectrum Disorder in Jamaican Children.
- Authors
Saroukhani, Sepideh; Samms-Vaughan, Maureen; Lee, MinJae; Bach, MacKinsey A.; Bressler, Jan; Hessabi, Manouchehr; Grove, Megan L.; Shakespeare-Pellington, Sydonnie; Loveland, Katherine A.; Rahbar, Mohammad H.
- Abstract
Mode of delivery, preterm birth, and low birth weight (LBW) are hypothesized to be associated with autism spectrum disorder (ASD) in the offspring. Using data from 343 ASD cases (2–8 years) and their age- and sex-matched typically developing controls in Jamaica we investigated these hypotheses. Our statistical analyses revealed that the parish of residence could modify the association between cesarean delivery and ASD, with a difference found in this relationship in Kingston parish [matched odds ratio (MOR) (95% confidence interval (CI)) 2.30 (1.17–4.53)] and other parishes [MOR (95% CI) 0.87 (0.48–1.59)]. Although the associations of LBW and preterm birth with ASD were not significant, we observed a significant interaction between LBW and the household socioeconomic status. These findings require replication.
- Subjects
JAMAICA; AUTISM; LOW birth weight; CESAREAN section; CONFIDENCE intervals; DELIVERY (Obstetrics); PREMATURE infants; MATERNAL health services; SOCIOECONOMIC factors; ODDS ratio
- Publication
Journal of Autism & Developmental Disorders, 2020, Vol 50, Issue 9, p3341
- ISSN
0162-3257
- Publication type
Article
- DOI
10.1007/s10803-019-04229-0