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- Title
Studies on the Effect of Social Stress on Measures of Disease Resistance in Laboratory Mice.
- Authors
Beden, Salem N.; Brain, P. F.
- Abstract
This article reports studies on the effect of social stress on measures of disease resistance in laboratory mice. Two experiments were carried out in which isolated male "TO" strain mice were exposed to trained fighters for brief periods and their immunological responses to subsequent sheep red blood cells (SRBC) challenge were assessed. The findings demonstrate that exposure to attack progressively reduces primary immune response to SRBC. Increasing exposure to defeat also, had little effect on secondary immune responses in which most antibody was 7S-mercaptoethanol-resistant antibody.
- Subjects
EFFECT of stress on natural immunity; LABORATORY mice; MICE behavior; PHYSIOLOGICAL stress; NATURAL immunity; IMMUNE response; ERYTHROCYTES; SHEEP
- Publication
Aggressive Behavior, 1982, Vol 8, Issue 2, p126
- ISSN
0096-140X
- Publication type
Article
- DOI
10.1002/1098-2337(1982)8:2<126::AID-AB2480080208>3.0.CO;2-9