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- Title
Effect of chlorhexidine gel on the prevention of alveolar osteitis and post‐operative pain following transalveolar extraction of impacted mandibular third molars: A randomized study.
- Authors
Erinoso, Olufemi; Ogunbayo, Olakunle; Adesina, Ayodele; James, Olutayo; Ladeinde, Akin; Ogunlewe, Olugbemiga; Olaitan, Ademola
- Abstract
Objective: This study aimed to compare the efficacy of 0.2% chlorhexidine gel with warm saline mouth rinse (WSMR) in the prevention of alveolar osteitis (AO) following transalveolar impacted mandibular third molar (IMTM) extraction after accounting for surgical operative confounding factors. Materials and Methods: We conducted a parallel design randomized study. Participants were consenting adults randomly assigned to 0.9% WSMR and 0.2% chlorhexidine gel (administered twice daily post‐operatively) groups. All participants were followed up daily post‐operatively for one week. The primary outcome was an incidence of AO, assessed using Blum's criteria. Fischer's exact tests and regression models were used to investigate the effect of interventions on AO. Results: One hundred participants were enrolled in the study, with 50 participants in each group. A higher incidence of AO was observed in the WSMR group than the chlorhexidine group (16% vs. 2%, p = 0.01). However, after adjusting for duration of extraction (aOR: 0.18; 95% CI: 0.02, 1.71) and bone operating time (aOR: 0.16; 95% CI: 0.02, 1.47), the difference was not statistically significant. Conclusions: In conclusion, the study demonstrates that the application of the 0.2% chlorhexidine gel was not significantly more effective in preventing AO compared with the use of WSMR following transalveolar IMTM extraction after controlling for operative factors.
- Subjects
THIRD molars; ALVEOLAR osteitis; POSTOPERATIVE pain; CHLORHEXIDINE; DENTAL extraction; MOUTHWASHES; ASEPSIS &; antisepsis
- Publication
Oral Surgery (1752-2471), 2024, Vol 17, Issue 2, p113
- ISSN
1752-2471
- Publication type
Article
- DOI
10.1111/ors.12857