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- Title
Durability of Response After Hepatitis B Surface Antigen Seroclearance During Nucleos(t)ide Analogue Treatment in a Multiethnic Cohort of Chronic Hepatitis B Patients: Results After Treatment Cessation.
- Authors
Heng Chi; Wong, David; Jie Peng; Jiawei Cao; Van Hees, Stijn; Vanwolleghem, Thomas; Xun Qi; Liang Chen; Feld, Jordan J.; de Knegt, Robert J.; Hansen, Bettina E.; Janssen, Harry L. A.
- Abstract
In 70 chronic hepatitis B patients with hepatitis B surface antigen seroclearance during nucleos(t)ide analogue therapy, response was sustained in all 54 patients who discontinued treatment. Clinically significant relapses as indicated by high hepatitis B virus DNA and ALT levels were not observed. Anti-HBs positivity may not be required to ensure sustained off-treatment response.
- Subjects
CHRONIC hepatitis B; HEPATITIS B virus; CELL surface antigens; NUCLEOSIDES; DISEASE relapse; THERAPEUTICS
- Publication
Clinical Infectious Diseases, 2017, Vol 65, Issue 4, p680
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/cix353