We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Juvenile xanthogranuloma in neurofibromatosis type 1. Prevalence and possible correlation with lymphoproliferative diseases: experience of a single center and review of the literature.
- Authors
Miraglia, E.; Laghi, A.; Iacovino, C.; Moramarco, A.; Giustini, S.
- Abstract
Neurofibromatosis type 1 (NF1), is a rare genetic disorder that may involve almost every organ system in the body such as cutaneous, ophthalmologic and central and peripheral nervous system. Cutaneous findings are usually the first sign of the disease. In this study, we investigate the real prevalence of xanthogranulomas juvenile (JXG) and possible correlation with lymphoproliferative diseases. This is a retrospective study conducted on a population with NF1 followed by February 1983 to February 2022 at the “Sapienza” University of Rome, Italy. We investigate the real prevalence of juvenile xanthogranuloma in NF1 and possible correlation with lymphoproliferative diseases. JXG was present in 39 cases (3.1%). JXG is more frequent in NF1 than in the general population while the possible association with lymphoproliferative diseases in NF1 remains controversial.
- Subjects
JUVENILE xanthogranuloma; NEUROFIBROMATOSIS 1; LYMPHOPROLIFERATIVE disorders; GENETIC disorders; PERIPHERAL nervous system
- Publication
Clinica Terapeutica, 2022, Vol 173, Issue 4, p353
- ISSN
0009-9074
- Publication type
Article
- DOI
10.7417/CT.2022.2445