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- Title
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases.
- Authors
Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Castellanos Otero, Paula; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; DeTure, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Björn; Gitler, Aaron D.; Dickson, Dennis W.
- Abstract
This letter demonstrates the potential of novel cryptic proteins resulting from TAR DNA-binding protein 43 (TDP-43) dysfunction as markers of TDP-43 pathology in neurodegenerative diseases.
- Subjects
NEURODEGENERATION; PATHOLOGY; DNA-binding proteins; PROTEINS; TAR
- Publication
Molecular Neurodegeneration, 2024, Vol 19, Issue 1, p1
- ISSN
1750-1326
- Publication type
Article
- DOI
10.1186/s13024-024-00718-8