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- Title
Human metapneumovirus infection among family members.
- Authors
MATSUZAKI, Y.; ITAGAKI, T.; IKEDA, T.; AOKI, Y.; ABIKO, C.; MIZUTA, K.
- Abstract
The transmission of human metapneumovirus (hMPV) among family members is not well understood. We identified 15 families in which multiple members were diagnosed with hMPV infection by real-time PCR in 2008 and 2010. Index patients ranged in age from 2 years to 11 years (median 5 years), and all 15 index cases were children who attended primary school, kindergarten, or nursery school. Contact patients ranged in age from 2 months to 46 years (median 6 years). Excluding five adult cases, contact patients were significantly younger than index patients (P = 0·0389). Of the 12 contact children, seven (58%) were infants who were taken care of at home. The serial interval between the onset of symptoms in an index patient and the onset of symptoms in a contact patient was estimated to be 5 days. These results suggest that the control of school-based outbreaks is important for preventing hMPV infection in infants.
- Subjects
SUDDEN onset of disease; EPIDEMICS; VIRUS disease transmission; INFANT diseases; POLYMERASE chain reaction; RESPIRATORY infections
- Publication
Epidemiology & Infection, 2013, Vol 141, Issue 4, p827
- ISSN
0950-2688
- Publication type
Article
- DOI
10.1017/S095026881200129X