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- Title
Risk of Parkinson's Disease in Celiac Disease: A Swedish Population‐Based Study.
- Authors
Kang, Xiaoying; Ploner, Alexander; Roelstraete, Bjorn; Ludvigsson, Jonas F.; Wirdefeldt, Karin
- Abstract
Using a population‐based matched cohort design, we assessed the association of celiac disease (CeD) with risk of PD by comparing patients with biopsy‐confirmed CeD in Sweden to a biopsy‐free population and their unaffected siblings, separately. No overall association was observed but CeD diagnosed before age 60 associated positively with incident diagnosis of PD (hazard ratio [HR] = 1.29; 95% confidence interval [CI]: 1.02–1.62), which was mainly attributed to the significantly elevated risk detected after 10–15 years since biopsy (HR = 1.68; 95% CI: 1.05–2.68). Our findings imply an increased vulnerability to long‐term PD development among patients with CeD diagnosed before 60s. ANN NEUROL 2023;94:911–916
- Subjects
SWEDEN; CELIAC disease; PARKINSON'S disease; CONFIDENCE intervals
- Publication
Annals of Neurology, 2023, Vol 94, Issue 5, p911
- ISSN
0364-5134
- Publication type
Article
- DOI
10.1002/ana.26780