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Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway.
- Published in:
- EMBO Molecular Medicine, 2010, v. 2, n. 12, p. 504, doi. 10.1002/emmm.201000103
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- Article
SP600125 Enhances Temperature-Controlled Repeated Thermal Stimulation-Induced Neurite Outgrowth in PC12-P1F1 Cells.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15602, doi. 10.3390/ijms232415602
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- Article
The Distinct Roles of LKB1 and AMPK in p53-Dependent Apoptosis Induced by Cisplatin.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 10064, doi. 10.3390/ijms231710064
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- Article
The E3 Ubiquitin-Protein Ligase RNF4 Promotes TNF-α-Induced Cell Death Triggered by RIPK1.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 5796, doi. 10.3390/ijms22115796
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- Article
Phosphinotripeptidic Inhibitors of Leucylaminopeptidases.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5090, doi. 10.3390/ijms22105090
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- Publication type:
- Article
BiFC Method Based on Intraorganellar Protein Crowding Detects Oleate-Dependent Peroxisomal Targeting of Pichia pastoris Malate Dehydrogenase.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4890, doi. 10.3390/ijms22094890
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- Article
Deubiquitinases: Modulators of Different Types of Regulated Cell Death.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4352, doi. 10.3390/ijms22094352
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- Article
Thromboembolic Adverse Drug Reactions in Janus Kinase (JAK) Inhibitors: Does the Inhibitor Specificity Play a Role?
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- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2449, doi. 10.3390/ijms22052449
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- Article
Kinase CDK2 in Mammalian Meiotic Prophase I: Screening for Hetero- and Homomorphic Sex Chromosomes.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1969, doi. 10.3390/ijms22041969
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- Article
OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1936, doi. 10.3390/ijms22041936
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- Article
Drosophila Homeodomain-Interacting Protein Kinase (Hipk) Phosphorylates the Hippo/Warts Signalling Effector Yorkie.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1862, doi. 10.3390/ijms22041862
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- Article
Update on the Roles of Rice MAPK Cascades.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1679, doi. 10.3390/ijms22041679
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- Article
Identification of Novel Substrates for cGMP Dependent Protein Kinase (PKG) through Kinase Activity Profiling to Understand Its Putative Role in Inherited Retinal Degeneration.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1180, doi. 10.3390/ijms22031180
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- Article
Differential Role of Threonine and Tyrosine Phosphorylation in the Activation and Activity of the Yeast MAPK Slt2.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1110, doi. 10.3390/ijms22031110
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- Article
TAK1 Mediates ROS Generation Triggered by the Specific Cephalosporins through Noncanonical Mechanisms.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 24, p. 9497, doi. 10.3390/ijms21249497
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- Article
Characterization of PC12 Cell Subclones with Different Sensitivities to Programmed Thermal Stimulation.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8356, doi. 10.3390/ijms21218356
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- Article
Post-Translational Modifications of the TAK1-TAB Complex.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 1, p. 205, doi. 10.3390/ijms18010205
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- Article
Brefeldin A-Inhibited Guanine Nucleotide-Exchange Factor 1 (BIG1) Governs the Recruitment of Tumor Necrosis Factor Receptor-Associated Factor 2 (TRAF2) to Tumor Necrosis Factor Receptor 1 (TNFR1) Signaling Complexes.
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- International Journal of Molecular Sciences, 2016, v. 17, n. 11, p. 1869, doi. 10.3390/ijms17111869
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- Article
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis.
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- Journal of Clinical Investigation, 2004, v. 114, n. 7, p. 937, doi. 10.1172/JCI200420317
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- Article
Preclinical validation of the new vitrification device possessing a feature of absorbing excess vitrification solution for the cryopreservation of human embryos.
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- Journal of Obstetrics & Gynaecology Research, 2020, v. 46, n. 2, p. 302, doi. 10.1111/jog.14176
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- Publication type:
- Article
Methylmercury directly modifies the 105th cysteine residue in oncostatin M to promote binding to tumor necrosis factor receptor 3 and inhibit cell growth.
- Published in:
- Archives of Toxicology, 2023, v. 97, n. 7, p. 1887, doi. 10.1007/s00204-023-03520-5
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- Publication type:
- Article
PXR stimulates growth factor-mediated hepatocyte proliferation by cross-talk with the FOXO transcription factor.
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- Biochemical Journal, 2016, v. 473, n. 3, p. 257, doi. 10.1042/BJ20150734
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- Publication type:
- Article
Involvement of ASK1 in Ca²+-induced p38 MAP kinase activation.
- Published in:
- EMBO Reports, 2004, v. 5, n. 2, p. 161, doi. 10.1038/sj.embor.7400072
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- Publication type:
- Article
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis.
- Published in:
- 2001
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- Publication type:
- Report
A comprehensive toxicological analysis of trans-fatty acids (TFAs) reveals a pro-apoptotic action specific to industrial TFAs counteracted by polyunsaturated FAs.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32083-9
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- Publication type:
- Article
The DEAH-Box RNA Helicase DHX15 Activates NF-κB and MAPK Signaling Downstream of MAVS During Antiviral Responses.
- Published in:
- Science Signaling, 2014, v. 7, n. 323, p. 1, doi. 10.1126/scisignal.2004841
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- Publication type:
- Article
Roquin-2 Promotes Ubiquitin-Mediated Degradation of ASK1 to Regulate Stress Responses.
- Published in:
- Science Signaling, 2014, v. 7, n. 309, p. 1, doi. 10.1126/scisignal.2004822
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- Publication type:
- Article
Industrially produced trans-fatty acids are potent promoters of DNA damage-induced apoptosis.
- Published in:
- Journal of Toxicological Sciences, 2024, v. 49, n. 1, p. 27, doi. 10.2131/jts.49.27
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- Publication type:
- Article
Redox cycling of 9,10-phenanthrenequinone activates epidermal growth factor receptor signaling through S-oxidation of protein tyrosine phosphatase 1B.
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- Journal of Toxicological Sciences, 2020, v. 45, n. 6, p. 349, doi. 10.2131/jts.45.349
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- Article
Pro-apoptotic functions of TRAF2 in p53-mediated apoptosis induced by cisplatin.
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- Journal of Toxicological Sciences, 2020, v. 45, n. 4, p. 219, doi. 10.2131/jts.45.219
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- Article
The anti-cancer drug gefitinib accelerates Fas-mediated apoptosis by enhancing caspase-8 activation in cancer cells.
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- Journal of Toxicological Sciences, 2019, v. 44, n. 6, p. 435
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- Publication type:
- Article
Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos.
- Published in:
- Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01838-2
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- Publication type:
- Article
Construction of three-dimensional liver tissue models by cell accumulation technique and maintaining their metabolic functions for long-term culture without medium change.
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- Journal of Biomedical Materials Research, Part A, 2015, v. 103, n. 4, p. 1554, doi. 10.1002/jbm.a.35292
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- Article
CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.
- Published in:
- EMBO Journal, 2010, v. 29, n. 15, p. 2501, doi. 10.1038/emboj.2010.141
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- Publication type:
- Article
trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59636-6
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- Publication type:
- Article
Efficient vitrification of mouse embryos using the Kitasato Vitrification System as a novel vitrification device.
- Published in:
- Reproductive Biology & Endocrinology, 2017, v. 15, p. 1, doi. 10.1186/s12958-017-0249-2
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- Publication type:
- Article
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines.
- Published in:
- Nature Immunology, 2010, v. 11, n. 1, p. 70, doi. 10.1038/ni.1819
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- Publication type:
- Article
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling.
- Published in:
- Nature Immunology, 2008, v. 9, n. 12, p. 1364, doi. 10.1038/ni.1678
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- Publication type:
- Article
Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production.
- Published in:
- Nature Immunology, 2007, v. 8, n. 1, p. 57, doi. 10.1038/ni1421
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- Publication type:
- Article
ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.
- Published in:
- Nature Immunology, 2005, v. 6, n. 6, p. 587, doi. 10.1038/ni1200
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- Publication type:
- Article
ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.
- Published in:
- Nature Communications, 2015, v. 6, n. 4, p. 6945, doi. 10.1038/ncomms7945
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- Publication type:
- Article
ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney.
- Published in:
- Nature Communications, 2012, v. 3, n. 12, p. 1285, doi. 10.1038/ncomms2283
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- Publication type:
- Article
The ASK1-MAP Kinase Cascades in Mammalian Stress Response.
- Published in:
- Journal of Biochemistry, 2004, v. 136, n. 3, p. 261, doi. 10.1093/jb/mvh134
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- Publication type:
- Article
Molecular Mechanisms of the Decision between Life and Death: Regulation of Apoptosis by Apoptosis Signal-Regulating Kinase 1.
- Published in:
- Journal of Biochemistry, 2001, v. 130, n. 1, p. 1, doi. 10.1093/oxfordjournals.jbchem.a002947
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- Publication type:
- Article
A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants.
- Published in:
- Annals of Neurology, 2012, v. 72, n. 5, p. 739, doi. 10.1002/ana.23668
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- Publication type:
- Article
Apoptosis Signal-Regulating Kinase 1-Mediated Signaling Pathway Regulates Nitric Oxide-Induced Activator Protein-1 Activation in Human Bronchial Epithelial Cells.
- Published in:
- American Journal of Respiratory & Critical Care Medicine, 2003, v. 167, n. 6, p. 856, doi. 10.1164/rccm.2204042
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- Publication type:
- Article
The polypeptide antibiotic polymyxin B acts as a pro-inflammatory irritant by preferentially targeting macrophages.
- Published in:
- Journal of Antibiotics, 2022, v. 75, n. 1, p. 29, doi. 10.1038/s41429-021-00490-7
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- Publication type:
- Article
Pro-caspase-3 protects cells from polymyxin B-induced cytotoxicity by preventing ROS accumulation.
- Published in:
- Journal of Antibiotics, 2019, v. 72, n. 11, p. 848, doi. 10.1038/s41429-019-0216-6
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- Publication type:
- Article
ASK1-dependent recruitment and activation of macrophages induce hair growth in skin wounds.
- Published in:
- Journal of Cell Biology, 2007, v. 176, n. 7, p. 903, doi. 10.1083/jcb.200611015
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- Publication type:
- Article
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89506-8
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- Publication type:
- Article