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- Title
Compensatory Growth Induced in Zebrafish Larvae after Pre-Exposure to a Microcystis aeruginosa Natural Bloom Extract Containing Microcystins.
- Authors
El Ghazali, Issam; Saqrane, Sanaa; Carvalho, Antonio Paulo; Ouahid, Youness; Oudra, Brahim; Del Campo, Francisca Fernandez; Vasconcelos, Vitor
- Abstract
Early life stage tests with zebrafish (Danio rerio) were used to detect toxic effects of compounds from a Microcystis aeruginosa natural bloom extract on their embryolarval development. We carried out the exposure of developing stages of fish to complex cyanobacterial blooms containing hepatotoxic molecules - microcystins. Fish embryo tests performed with the bloom extract containing 3 mg·L-1 Eq microcystin-LR showed that after 24 h of exposure all fish embryos died. The same tests performed with other diluted extracts (containing 0.3, 0.1 and 0.03 mg·L-1 Eq microcystin-LR) were shown to have an influence on zebrafish development and a large number of embryos showed malformation signs (edema, bent and curving tail). After hatching the larvae were transferred to a medium without toxins to follow the larval development under the new conditions. The specific growth of the pre-exposed larvae was significantly more important than that of the control larvae. This may represent a compensatory growth used to reduce the difference in size with the control fish noted after hatching.
- Subjects
ZEBRA danio; MICROCYSTIS aeruginosa; CYANOBACTERIA; MOLECULES; TOXINS; OSCILLATORIA; RAINBOW trout; STEELHEAD trout; FISHES
- Publication
International Journal of Molecular Sciences, 2009, Vol 10, Issue 1, p133
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms10010133