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- Title
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches.
- Authors
Ferrari, P. C.; Araujo, F. F.; Pianaro, S. A.
- Abstract
Halloysite nanotubes (HNTs) are aluminosilicate nanoclay mineral which have a hollow tubular structure and occurs naturally. They are biocompatible and viable carrier for inclusion of biologically active molecules due to the empty space inside the tubular structure. In this article, the HNTs main characteristics, and the HNTs-polymeric nanocomposite formation and their potential application as improvement of the mechanical performance of polymers and entrapment of hydrophilic and lipophilic substances are summarized. Recent works covering the increment of HNTs-polymeric nanocomposites and presenting promising employment of these systems as nanosized carrier, being suitable for pharmaceutical and biomedical applications, based on earlier evidence in literature of its nature to sustain the release of loaded drugs, presenting low cytotoxicity, and providing evidence for controlled drug delivery are reviewed.
- Subjects
HALLOYSITE; DRUG delivery systems; POLYMERIC nanocomposites; CONTROLLED release drugs; BIOACTIVE compounds; ALUMINUM silicates
- Publication
Ceramica, 2017, Vol 63, Issue 368, p423
- ISSN
0366-6913
- Publication type
Article
- DOI
10.1590/0366-69132017633682167