We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Selected neurological complications of oncological treatment -- literature overview.
- Authors
Gorzelak-Magiera, Anita; Bobola, Agnieszka; Robek, Amanda; Krzystanek, Ewa; Gisterek, Iwona
- Abstract
Treatment in oncology may lead to several adverse side effects, including those affecting the nervous system. These side effects may reduce the quality of life of patients, both during and after treatment, and may necessitate changes in the treatment regimen or reduction of drug doses, thus reducing the effectiveness of therapy. The knowledge of therapy-induced side effects is essential for their early recognition and differentiation from symptoms resulting from the progression of neoplastic disease, metabolic disorders, or infections, requiring prompt initiation of causal treatment. This article presents the current state of knowledge regarding central and peripheral neurotoxicity of treatment in oncology. Adverse effects described after chemo- and radiotherapy are better known but still limit the potential possibilities of the applied treatment. Neurotoxicities of targeted therapy and immunotherapy, which are of increasing importance in the era of personalization of treatment, are presented.
- Subjects
NEUROTOXICOLOGY; CANCER chemotherapy; OTOTOXICITY; METABOLIC disorders; QUALITY of life
- Publication
Oncology in Clinical Practice (2450-1654), 2023, Vol 19, Issue 5, p346
- ISSN
2450-1654
- Publication type
Article
- DOI
10.5603/OCP.2022.0032